Glucose-6-Phosphate Dehydrogenase Antikörper (AA 321-420)

Produktnummer ABIN1386785

Der Kaninchen Polyklonal Anti-Glucose-6-Phosphate Dehydrogenase-Antikörper wurde für ELISA, IHC (p) und IHC (fro) validiert. Er ist geeignet, Glucose-6-Phosphate Dehydrogenase in Proben von Human zu detektieren.

Kurzübersicht für Glucose-6-Phosphate Dehydrogenase Antikörper (AA 321-420) (ABIN1386785)

Target: Glucose-6-Phosphate Dehydrogenase (G6PD)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glucose-6-Phosphate Dehydrogenase Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-Glucose-6-Phosphate Dehydrogenase Antikörper

Bindungsspezifität: AA 321-420

Homologie: Human,Mouse,Rat,Dog,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human G6PDH

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu Glucose-6-Phosphate Dehydrogenase

Target: Glucose-6-Phosphate Dehydrogenase (G6PD)

Andere Bezeichnung: G6PDH

Hintergrund:

Synonyms: 6 phosphogluconolactonase, 6-phosphogluconolactonase, 6PGL, H6PD, DKFZp686A01246, G6PD H form, G6PDH, G6PE_HUMAN, GDH, H6PD, GDH/6PGL endoplasmic bunctional protein, Glucose 1 dehydrogenase, Glucose 6 phosphate dehydrogenase salivary, Glucose dehyrogenase, Gpd1, H6pd, Hexose 6 phosphate dehydrogenase, Hexose-6-phosphate dehydrogenase, MGC87643.

Background: H6PD (hexose-6-phosphate dehydrogenase, GDH/6PGL endoplasmic bifunctional protein) is a 789 amino acid protein encoded by the human gene H6PD. The N-terminal section of H6PD belongs to the glucose-6-phosphate dehydrogenase family, while the C-terminal section belongs to the glucosamine/galactosamine-6-phosphate isomerase family, 6-phosphogluconolactonase subfamily. H6PD is responsible primarily for the oxidation of glucose-6-phosphate and glucose. It also oxidizes other hexose-6-phosphates. H6PD catalyzes the conversion of glucose 6-phosphate to 6-phosphogluconolactone within the lumen of the endoplasmic reticulum, thereby generating reduced nicotinamide adenine dinucleotide phosphate. Reduced nicotinamide adenine dinucleotide phosphate is a necessary cofactor for the reductase activity of 11-hydroxysteroid dehydrogenase type 1, which converts hormonally inactive cortisone to active cortisol (in rodents, 11-dehydrocorticosterone to corticosterone).

Gen-ID: 9563

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones