POU3F3 Antikörper (AA 351-450)

Produktnummer ABIN1386623

Der Kaninchen Polyklonal Anti-POU3F3-Antikörper wurde für WB, ELISA, ICC, IF (cc), IF (p), IHC (fro) und IHC (p) validiert. Er ist geeignet, POU3F3 in Proben von Human zu detektieren.

Kurzübersicht für POU3F3 Antikörper (AA 351-450) (ABIN1386623)

Target: POU3F3 (POU Class 3 Homeobox 3 (POU3F3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POU3F3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-POU3F3 Antikörper

Bindungsspezifität: AA 351-450

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Brain1/POU3F3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu POU3F3

Target: POU3F3 (POU Class 3 Homeobox 3 (POU3F3))

Andere Bezeichnung: Brain1/POU3F3

Hintergrund:

Synonyms: Brain 1, Brain specic homeobox/POU domain protein 1, Brain-1, Brain-specic homeobox/POU domain protein 1, Brain1, BRN 1, Brn-1, BRN1, class 3, Oct-8, Octamer-binding protein 8, Octamer-binding transcription factor 8, OTF 8, OTF-8, OTF8, PO3 F3, PO3F 3, PO3F3, PO3F3_HUMAN, POU class 3 homeobox 3, POU domain, POU domain, class 3, transcription factor 3, POU3 F3, POU3F 3, Pou3f3, RHS 1, Rhs 2, RHS1, Rhs2, Skin 1, Skin1, transcription factor 3.

Background: The Brn family of transcription factors are found in a highly restricted subset of neurons and are critical to the early embryonic development of the central nervous system. Brn-1 and Brn-2 are class III POU domain proteins. Expressed during the development of the forebrain and coexpressed in most layer II-V cortical neurons, Brn-1 and Brn-2 appear to critically control the initiation of radial migration of cortical neurons. Brn-2 is thought to be involved in smooth muscle cell development and differentiation. Brn-3 is a class IV POU domain protein. Three Brn-3 proteins have been described and are designated Brn-3a, Brn-3b and Brn-3c. Brn-3a has two functional transactivating domains, one at the amino terminus and one at the carboxy terminus. While Brn-3a and Brn-3c stimulate transcription, Brn-3b generally functions as a transcriptional repressor. However, Brn-3b, but not Brn-3a, has been shown to regulate the expression of the acetylcholine receptor.