BPTF Antikörper (AA 2801-3046)

Produktnummer ABIN1386560

Der Kaninchen Polyklonal Anti-BPTF-Antikörper wurde für WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) und ICC validiert. Er ist geeignet, BPTF in Proben von Maus und Ratte zu detektieren.

Kurzübersicht für BPTF Antikörper (AA 2801-3046) (ABIN1386560)

Target: BPTF (Bromodomain PHD Finger Transcription Factor (BPTF))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BPTF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Produktdetails anti-BPTF Antikörper

Bindungsspezifität: AA 2801-3046

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Cow,Sheep,Pig,Chicken,Rabbit,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BPTF/FALZ

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu BPTF

Target: BPTF (Bromodomain PHD Finger Transcription Factor (BPTF))

Andere Bezeichnung: BPTF/FALZ

Hintergrund:

Synonyms: Bromodomain and PHD finger containing transcription factor, Bromodomain PHD finger transcription factor, FAC 1, BPTF / FALZ, fac1, FALZ, Fetal Alz 50 clone 1 protein, Fetal Alz 50 reactive clone 1, Fetal Alzheimer antigen, Nucleosome remodeling factor, Nucleosome remodeling factor subunit BPTF, Nucleosome remodeling factor, large subunit, NURF 301, NURF301.

Background: BPTF is a 2,907 amino acid protein encoded by the human gene BPTF. BPTF belongs to the PBTF family and contains one bromodomain, one DDT domain and two PHD-type zinc fingers. BPTF acts as a histone-binding component of NURF (nucleosome-remodeling factor). The NURF complex, which consists of SMARCA1, BPTF, RbAp46 and RbAp48, acts to catalyze ATP-dependent nucleosome sliding and facilitates transcription of chromatin. It specifically recognizes histone H3 tails trimethylated on 'Lys-4' (H3-K4Me3), which mark transcription start sites of virtually all active genes. BPTF may also help regulate transcription through direct binding to DNA or transcription factors.