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C1QBP Antikörper (AA 101-200)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch C1QBP in WB, ICC, ELISA, IF (cc), IF (p), IHC (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Maus.
Produktnummer ABIN1386484

Kurzübersicht für C1QBP Antikörper (AA 101-200) (ABIN1386484)

Target

Alle C1QBP Antikörper anzeigen
C1QBP (Complement Component 1, Q Subcomponent Binding Protein (C1QBP))

Reaktivität

  • 94
  • 45
  • 33
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Maus

Wirt

  • 100
  • 28
  • 1
Kaninchen

Klonalität

  • 89
  • 40
Polyklonal

Konjugat

  • 80
  • 14
  • 14
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser C1QBP Antikörper ist unkonjugiert

Applikation

  • 105
  • 55
  • 38
  • 31
  • 25
  • 20
  • 17
  • 12
  • 12
  • 7
  • 6
  • 6
  • 4
  • 3
  • 3
  • 2
  • 2
Western Blotting (WB), Immunocytochemistry (ICC), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 19
    • 14
    • 12
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200

    Kreuzreaktivität

    Maus

    Homologie

    Human,Rat,Dog,Sheep,Pig

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human C1QBP

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Target

    C1QBP (Complement Component 1, Q Subcomponent Binding Protein (C1QBP))

    Andere Bezeichnung

    C1QBP/GC1q R

    Hintergrund

    Synonyms: C1q globular domain binding protein, C1QBP, C1QBP_HUMAN antibody Complement component 1 q subcomponent binding protein, Complement component 1 Q subcomponent binding protein mitochondrial, Complement component 1 Q subcomponent-binding protein, mitochondrial, GC1Q R, GC1q R protein, GC1q-R protein, GC1QBP, GC1QR, Glycoprotein gC1qBP, HABP 1, HABP1, Hyaluronan binding protein 1, Hyaluronan-binding protein 1, Mitochondrial matrix protein p32, p32 antibody p33 antibody Pre mrna splicing factor SF2 P32 subunit precursor, SF2p32, Splicing factor SF2 associated protein.

    Background: The human complement subcomponent C1q associates with C1r and C1s in order to yield the first component of the serum complement system (SCS). The SCS contains over 30 glycoproteins that influence physiological mechanisms of the body in response to immune complex (the classical pathway), carbohydrate (the lectin pathway) or bacterial (alternative pathway) initiation. C1q binding protein (C1QBP), also designated gC1q-R, p32 (p33) or HABP1 (hyaluronan-binding protein 1), is known to bind the globular heads of C1q molecules and inhibit C1 activation. C1QBP has been described as a complement receptor for C1q on B cells, neutrophils and mast cells. The C1QBP protein may form homodimers. C1QBP is expressed in vascular endothelial cells and has been found to be a multifunctional protein interacting with elements of complement, coagulation and kinin systems. In addition, C1QBP is a subunit of pre-mRNA splicing factor SF2/ASF.

    Pathways

    Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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