ATRAID Antikörper

Produktnummer ABIN1386345

Der Kaninchen Polyklonal anti-ATRAID Antikörper (ABIN1386345) detektiert spezifisch ATRAID in WB, IF (p) und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für ATRAID Antikörper (ABIN1386345)

Target: ATRAID (All-Trans Retinoic Acid-Induced Differentiation Factor (ATRAID))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATRAID Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-ATRAID Antikörper

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C2orf28

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu ATRAID

Target: ATRAID (All-Trans Retinoic Acid-Induced Differentiation Factor (ATRAID))

Andere Bezeichnung: C2orf28

Hintergrund:

Synonyms: Apoptosis related protein 3, Apoptosis related protein APR 3, APR 3, APR3, Chromosome 2 open reading frame 28, HSPC013, p18, PRO240, ARAID_HUMAN.

Background: APR3, also known as C2orf28 or p18, is a 229 amino acid single-pass membrane protein that contains one EGF-like domain and exists as two alternatively spliced isoforms. Expressed at a low level in hematopoietic cell lines, APR3 is thought to be involved in apoptosis and may also play a role in hematopoietic development and differentiation. The gene encoding APR3 maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8 % of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes. Additionally, an extremely rare recessive genetic disorder, Alstr syndrome, is caused by mutations in the ALMS1 gene, which maps to chromosome 2.