GRIK5 Antikörper (AA 201-300)

Produktnummer ABIN1386332

Der Kaninchen Polyklonal Anti-GRIK5-Antikörper wurde für WB, ELISA, IF (cc), IF (p), IHC (p), ICC und IHC (fro) validiert. Er ist geeignet, GRIK5 in Proben von Human zu detektieren.

Kurzübersicht für GRIK5 Antikörper (AA 201-300) (ABIN1386332)

Target: GRIK5 (Glutamate Receptor, Ionotropic, Kainate 5 (GRIK5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRIK5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-GRIK5 Antikörper

Bindungsspezifität: AA 201-300

Homologie: Human,Mouse,Rat,Dog,Sheep,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GRIK5/KA2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu GRIK5

Target: GRIK5 (Glutamate Receptor, Ionotropic, Kainate 5 (GRIK5))

Andere Bezeichnung: GRIK5/KA2

Hintergrund:

Synonyms: EAA 2, EAA2, Excitatory amino acid receptor 2, GluRgamma2, Glutamate receptor, Glutamate receptor KA 2, Glutamate receptor KA-2, Glutamate receptor KA2, Glutamate receptor, ionotropic kainate 5 [Precursor], Glutamate receptor, ionotropic, kainate 5 gamma 2, Glutamate receptor, ionotropic, kainate 5, GRIK 2, GRIK 5, GRIK2, Grik5, GRIK5_HUMAN, iGlu5, ionotropic kainate 5, KA2, MGC118086.

Background: Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of the structurally related subunits GluR-1 to -7, KA1 and KA2. KA1 (also designated EEA1) and KA2 (also designated EEA2) form heteromeric receptors with GluR subunits when coexpressed, forming ion channels with various properties. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate.

Pathways: Carbohydrate Homeostasis, Synaptic Membrane, Maintenance of Protein Location, Synaptic Vesicle Exocytosis