ADRA2C Antikörper (AA 21-120)

Produktnummer ABIN1386323

Produktdetails anti-ADRA2C Antikörper

Target: ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))

Bindungsspezifität: AA 21-120

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADRA2C Antikörper ist unkonjugiert

Applikation: ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ADRA2C/alpha 2C Adrenergic Receptor

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu ADRA2C

Target: ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))

Andere Bezeichnung: ADRA2C/alpha 2C Adrenergic Receptor (ADRA2C Produkte)

Synonyme: ADRA2L2 antikoerper, ADRA2RL2 antikoerper, ADRARL2 antikoerper, ALPHA2CAR antikoerper, Adra-2c antikoerper, [a]2C antikoerper, alpha2-C4 antikoerper, alpha2C antikoerper, zgc:194523 antikoerper, zgc:194541 antikoerper, adra2c antikoerper, ADRA2B antikoerper, ADRA2C antikoerper, adrenoceptor alpha 2C antikoerper, adrenergic receptor, alpha 2c antikoerper, ADRA2C antikoerper, Adra2c antikoerper, adra2c antikoerper

Hintergrund:

Synonyms: Adra 2c, Adra 2c, ADRA2C, ADRA2C, ADRA2L2, ADRA2L2, ADRA2RL2, ADRA2RL2, ADRARL2, ADRARL2, Adrenergic alpha 2C receptor, Adrenoceptor alpha 2C, Alpha 2C adrenergic receptor, Alpha 2C adrenergic receptor subtype C4, Alpha 2C adrenoceptor, Alpha 2C adrenoreceptor, Alpha 2CAR, alpha2 AR C4, alpha2 AR C4, alpha2 C4, alpha2 C4, alpha2C, alpha2C, ALPHA2CAR, alpha2cii-adrenergic receptor, Subtype alpha2 C4, Subtype alpha2 C4, ADA2C_HUMAN.

Background: alpha2C-adrenergic receptors (alpha2C-AR) regulate neurotransmitter release from sympathetic nerves in the heart, and from adrenergic neurons in the central nervous system. alpha2C-AR can influence Parkinson?s disease, panic disorders, and Huntington disease (HD) progression. A genetic variant in the alpha2C-AR coding region (Del322-325) renders the receptor partially uncoupled from Gi, and is a contributing risk factor for heart failure. alpha2C-AR transcripts are present in rat muscle, heart, pancreas, and kidney.

Pathways: EGFR Signaling Pathway, cAMP Metabolic Process