TWF2 Antikörper (AA 51-150)

Produktnummer ABIN1386208

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch TWF2 in WB, IHC (p), IF (cc), IF (p) und IHC (fro). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für TWF2 Antikörper (AA 51-150) (ABIN1386208)

Target: TWF2 (Twinfilin, Actin-Binding Protein, Homolog 2 (Drosophila) (TWF2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TWF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-TWF2 Antikörper

Bindungsspezifität: AA 51-150

Verwendungszweck: TWF2 Polyclonal Antibody

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TWF2/PTK9L

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:300-5000),

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu TWF2

Target: TWF2 (Twinfilin, Actin-Binding Protein, Homolog 2 (Drosophila) (TWF2))

Andere Bezeichnung: TWF2/PTK9L

Hintergrund:

Synonyms: A6 related protein, A6r, A6RP, hA6RP, MSTP011, Protein tyrosine kinase 9 like, PTK 9L, PTK9L,PTK9L, PTK9L protein tyrosine kinase 9 like, TWF 2, Twinfilin 1 like protein, Twinfilin 2, Twinfilin actin binding protein homolog 2, Twinfilin like protein, Twinfilin2, TWF2_HUMAN.

Background: Twinfilin-2 is a 349 amino acid protein that localizes to the perinuclear region of the cytoplasm, as well as to the cytoskeleton, and contains two ADF-H domains. Expressed ubiquitously, Twinfilin-2 functions as an Actin-binding protein that is able to both bind and sequester G-Actin and cap the barbed ends of Actin filaments, thereby inhibiting Actin polymerization and playing a role in Actin-related motile and morphological processes. Twinfilin-2 is subject to post-translational phosphorylation by PKC zeta. The gene encoding Twinfilin-2 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.

Pathways: Regulation of Actin Filament Polymerization, Regulation of Cell Size, Maintenance of Protein Location, Toll-Like Receptors Cascades