EBI3 Antikörper (AA 121-229)

Produktnummer ABIN1386189

Dieser Anti-EBI3 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von EBI3 in ELISA, ICC, IHC (p), IF (cc), IF (p) und IHC (fro). Geeignet für Human.

Kurzübersicht für EBI3 Antikörper (AA 121-229) (ABIN1386189)

Target: EBI3 (IL-27b) (Interleukin-27 subunit beta (IL-27b))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EBI3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-EBI3 Antikörper

Bindungsspezifität: AA 121-229

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EBI3/IL-27beta

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu EBI3

Target: EBI3 (IL-27b) (Interleukin-27 subunit beta (IL-27b))

Andere Bezeichnung: IL-27beta

Hintergrund:

Synonyms: cytokine receptor, EBI3, EBV induced gene 3 protein, EBV-induced gene 3 protein, Epstein Barr virus induced 3, Epstein Barr virus induced gene 3, Epstein Barr virus induced gene 3 protein, Epstein-Barr virus-induced gene 3 protein, IL 27 subunit beta, IL 27B, IL-27 subunit beta, IL-27B, IL27 subunit, IL27 subunit beta, IL27B, IL27B_HUMAN, IL35 subunit, interleukin 27 subunit beta, Interleukin-27 subunit beta.

Background: Epstein-Barr virus-induced gene 3 (Ebi3) is a widely expressed homolog to the interleukin IL-12 p40 subunit protein that forms a heterodimer with either IL-12 p35 or an IL-12 p35 homolog, p28, to create a new cytokine (IL-27). Ebi3 may function to antagonize IL-12 and to inhibit the development of a Th1 immune response. Ebi3 is strongly expressed in Hodgkin and Reed-Sternberg cells, independently of the EBV status of the tumor cells. Ebi2 is expressed in B-lymphocytes and lymphoid tissues and may function in the modulation of the immune system. Out of the nine genes that are induced by the Epstein-Barr virus, Ebi2 exhibits the highest levels of up-regulation. In addition, Ebi2 may play a role mediating normal lymphocyte functions.