FBXO21 Antikörper
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- Target Alle FBXO21 Antikörper anzeigen
- FBXO21 (F-Box Protein 21 (FBXO21))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FBXO21 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human FBXO21
- Isotyp
- IgG
- Top Product
- Discover our top product FBXO21 Primärantikörper
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anti-F-Box Protein 21 (FBXO21) antibody
FBXO21 Reaktivität: Human, Maus, Ratte, Affe WB, IHC, IF, FACS, IHC (p) Wirt: Maus Monoclonal 5H4 unconjugated
anti-F-Box Protein 21 (FBXO21) antibodyFBXO21 Reaktivität: Human, Maus, Ratte, Hund, Affe WB, IHC, IF, FACS, IHC (p) Wirt: Maus Monoclonal 2C7 unconjugated
anti-F-Box Protein 21 (FBXO21) (AA 440-621) antibodyFBXO21 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-F-Box Protein 21 (FBXO21) (AA 474-501), (C-Term) antibodyFBXO21 Reaktivität: Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB18234 unconjugated
anti-F-Box Protein 21 (FBXO21) antibodyFBXO21 Reaktivität: Human, Maus, Ratte WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-F-Box Protein 21 (FBXO21) (AA 74-123) antibodyFBXO21 Reaktivität: Human, Maus, Ratte, Hund, Affe, Kaninchen, Rind (Kuh), Hamster, Schwein, Fledermaus WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-F-Box Protein 21 (FBXO21) (AA 1-621) antibodyFBXO21 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-F-Box Protein 21 (FBXO21) (C-Term) antibodyFBXO21 Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Meerschweinchen, Pferd WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-F-Box Protein 21 (FBXO21) (N-Term) antibodyFBXO21 Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Meerschweinchen, Rind (Kuh), Saccharomyces cerevisiae WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-F-Box Protein 21 (FBXO21) (AA 474-503), (C-Term) antibodyFBXO21 Reaktivität: Human, Maus WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- FBXO21 (F-Box Protein 21 (FBXO21))
- Andere Bezeichnung
- FBXO21 (FBXO21 Produkte)
- Synonyme
- FBX21 antikoerper, 2810425J22Rik antikoerper, AU016673 antikoerper, mKIAA0875 antikoerper, si:ch211-42a13.2 antikoerper, F-box protein 21 antikoerper, FBXO21 antikoerper, Fbxo21 antikoerper, fbxo21 antikoerper
- Hintergrund
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Synonyms: F box only protein 21, F box protein 21, F-box only protein 21, FBX21, FBX21_HUMAN, Fbxo21, FLJ90233, KIAA0875, MGC26682.
Background: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Has some glucocorticoid receptor-responsive activity.
- Gen-ID
- 23014
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