ICA1 Antikörper (AA 1-100)

Produktnummer ABIN1385898

Dieses Anti-ICA1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ICA1 in WB, ELISA, ICC, IF (cc), IF (p), IHC (p) und IHC (fro). Geeignet für Human.

Kurzübersicht für ICA1 Antikörper (AA 1-100) (ABIN1385898)

Target: ICA1 (Islet Cell Autoantigen 1, 69kDa (ICA1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ICA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-ICA1 Antikörper

Bindungsspezifität: AA 1-100

Homologie: Human,Mouse,Rat,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ICA1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu ICA1

Target: ICA1 (Islet Cell Autoantigen 1, 69kDa (ICA1))

Andere Bezeichnung: ICA1

Hintergrund:

Synonyms: 69 kDa islet cell autoantigen, Diabetes mellitus type I autoantigen, ICA 1, ICA1, ICA69, ICA69_HUMAN, ICAp69, Islet cell autoantigen 1 69kD, Islet cell autoantigen 1 69 kDa, Islet cell autoantigen 1, Islet cell autoantigen 1 isoform, Islet cell autoantigen p69, OTTHUMP00000200933, OTTHUMP00000200934, OTTHUMP00000200941, OTTHUMP00000200993, p69.

Background: Carbonic anhydrases (CAs), also designated carbonate dehydratases or carbonate hydrolyases, form a large family of genes that encode zinc metalloenzymes of great physiologic importance. As catalysts of the reversible hydration of carbon dioxide, these enzymes participate in a variety of biologic processes, including respiration, acid-base balance, bone resorption and calcification as well as the formation of aqueous humor, cerebrospinal fluid, saliva and gastric acid. Genes in the ?carbonic anhydrase family encode either active carbonic anhydrase isozymes or _catalytic?(devoid of CO2 hydration activity) carbonic anhydrase-related proteins. Human CA I (CA1) is encoded by the CA1 gene, which maps to a region on chromosome 8 that harbors a cluster of CA genes. CA I localizes to the cytoplasm and research indicates that a severe deficiency of CA I does not result in any obvious hematological or renal consequences.