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PICALM Antikörper (AA 251-350)

Dieses Anti-PICALM-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PICALM in WB, ELISA, IF (cc), IF (p), IHC (p), ICC und IHC (fro). Geeignet für Maus und Ratte.
Produktnummer ABIN1385889

Kurzübersicht für PICALM Antikörper (AA 251-350) (ABIN1385889)

Target

Alle PICALM Antikörper anzeigen
PICALM (Phosphatidylinositol Binding clathrin Assembly Protein (PICALM))

Reaktivität

  • 27
  • 24
  • 24
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
Maus, Ratte

Wirt

  • 38
  • 3
Kaninchen

Klonalität

  • 39
  • 2
Polyklonal

Konjugat

  • 23
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser PICALM Antikörper ist unkonjugiert

Applikation

  • 36
  • 12
  • 12
  • 10
  • 8
  • 5
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 14
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 251-350

    Kreuzreaktivität

    Maus, Ratte

    Homologie

    Human,Dog,Cow,Sheep,Horse,Zebrafish

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human PICALM/CALM

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Target

    PICALM (Phosphatidylinositol Binding clathrin Assembly Protein (PICALM))

    Andere Bezeichnung

    PICALM/CALM

    Hintergrund

    Synonyms: Clathrin assembly lymphoid myeloid leukemia, Clathrin assembly lymphoid myeloid leukemia protein, CLTH, LAP, Phosphatidylinositol-binding clathrin assembly protein, PICAL_HUMAN, PICALM.

    Background: Clathrin-coated pits and vesicles are assembled for receptor-mediated endocytosis through interaction with clathrin associated protein complexes. Vesicle transport is mediated from the trans-Golgi network by the adapter complex AP-1 and from the plasma membrane by the AP-2 complex. The AP-1 and AP-2 adapter protein complexes consist of clathrin binding adaptin proteins and two smaller subunits known as AP50 and AP17. The Alpha- and Beta-Adaptin chains have a similar two-domain organization with C-terminal domains that vary in both sequence and length. Alpha-Adaptin splice variants A and C display variable relative expression levels and differential distribution in different tissues. AP180 (also designated AP-3 or F1-20) is a synapse-specific clathrin assembly protein. The protein CALM (clathrin assembly protein lymphoid myeloid leukemia) is highly homologous to AP180 and may also be involved in clathrin assembly.

    Pathways

    Synaptic Membrane
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