RENT1/UPF1 Antikörper (AA 301-450)
Quick Overview for RENT1/UPF1 Antikörper (AA 301-450) (ABIN1385864)
Target
Alle RENT1/UPF1 (UPF1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 301-450
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Homologie
- Human,Mouse,Rat,Dog,Cow,Horse,Chicken
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human RENT1/hUPF1
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Isotyp
- IgG
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Applikationshinweise
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Haltbarkeit
- 12 months
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- RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))
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Andere Bezeichnung
- RENT1/hUPF1
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Hintergrund
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Synonyms: ATP dependent helicase RENT1, ATP-dependent helicase RENT1, Delta helicase, HUPF 1, HUPF1, KIAA0221, Nonsense mRNA reducing factor 1, NORF 1, NORF1, pNORF 1, pNORF1, Regulator of nonsense transcripts 1, RENT 1, RENT1, RENT1_HUMAN, Smg 2, Smg 2 homolog nonsense mediated mRNA decay factor, UP Framesht 1, Up framesht mutation 1 homolog S. cerevisiae, Up framesht mutation 1 homolog, Up framesht suppressor 1 homolog, Up-framesht mutation 1 homolog S. cerevisiae, Up-framesht suppressor 1 homolog, UPF 1, UPF 1 regulator of nonsense transcripts homolog, UPF1.
Background: In eukaryotes, it is essential to have the ability to detect and degrade transcripts that lack full coding potential. Nonsense-mediated RNA decay (NMD) protects the organism by avoiding the translation of truncated peptides with dominant negative or deleterious gain-of-function potential. Rent1, a mammalian ortholog of Upflp, is essential for embryonic viability (13). Rent1 (also designated regulator of nonsense transcripts and HUpf1) contains an N-terminal zinc finger-like domain, NTPase domains and a region comprised of domains that define Rent1 as a superfamily group I helicase.
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Gen-ID
- 5976
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Pathways
- SARS-CoV-2 Protein Interaktom
Target
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