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RENT1/UPF1 Antikörper (AA 301-450)

This anti-RENT1/UPF1 antibody (ABIN1385864) is a Rabbit Polyclonal antibody detecting RENT1/UPF1 in ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro). Suitable for Human.
Produktnummer ABIN1385864

Quick Overview for RENT1/UPF1 Antikörper (AA 301-450) (ABIN1385864)

Target

Alle RENT1/UPF1 (UPF1) Antikörper anzeigen
RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))

Reaktivität

  • 55
  • 17
  • 7
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 48
  • 4
  • 3
Kaninchen

Klonalität

  • 47
  • 8
Polyklonal

Konjugat

  • 31
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser RENT1/UPF1 Antikörper ist unkonjugiert

Applikation

  • 28
  • 16
  • 13
  • 13
  • 11
  • 10
  • 7
  • 6
  • 5
  • 3
  • 2
  • 1
  • 1
ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 14
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 301-450

    Homologie

    Human,Mouse,Rat,Dog,Cow,Horse,Chicken

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human RENT1/hUPF1

    Isotyp

    IgG
  • Applikationshinweise

    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Target

    RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))

    Andere Bezeichnung

    RENT1/hUPF1

    Hintergrund

    Synonyms: ATP dependent helicase RENT1, ATP-dependent helicase RENT1, Delta helicase, HUPF 1, HUPF1, KIAA0221, Nonsense mRNA reducing factor 1, NORF 1, NORF1, pNORF 1, pNORF1, Regulator of nonsense transcripts 1, RENT 1, RENT1, RENT1_HUMAN, Smg 2, Smg 2 homolog nonsense mediated mRNA decay factor, UP Framesht 1, Up framesht mutation 1 homolog S. cerevisiae, Up framesht mutation 1 homolog, Up framesht suppressor 1 homolog, Up-framesht mutation 1 homolog S. cerevisiae, Up-framesht suppressor 1 homolog, UPF 1, UPF 1 regulator of nonsense transcripts homolog, UPF1.

    Background: In eukaryotes, it is essential to have the ability to detect and degrade transcripts that lack full coding potential. Nonsense-mediated RNA decay (NMD) protects the organism by avoiding the translation of truncated peptides with dominant negative or deleterious gain-of-function potential. Rent1, a mammalian ortholog of Upflp, is essential for embryonic viability (13). Rent1 (also designated regulator of nonsense transcripts and HUpf1) contains an N-terminal zinc finger-like domain, NTPase domains and a region comprised of domains that define Rent1 as a superfamily group I helicase.

    Gen-ID

    5976

    Pathways

    SARS-CoV-2 Protein Interaktom
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