RENT1/UPF1 Antikörper (AA 301-450)

Produktnummer ABIN1385864

Produktdetails anti-RENT1/UPF1 Antikörper

Target: RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))

Bindungsspezifität: AA 301-450

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RENT1/UPF1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RENT1/hUPF1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu RENT1/UPF1

Target: RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))

Andere Bezeichnung: RENT1/hUPF1 (UPF1 Produkte)

Hintergrund:

Synonyms: ATP dependent helicase RENT1, ATP-dependent helicase RENT1, Delta helicase, HUPF 1, HUPF1, KIAA0221, Nonsense mRNA reducing factor 1, NORF 1, NORF1, pNORF 1, pNORF1, Regulator of nonsense transcripts 1, RENT 1, RENT1, RENT1_HUMAN, Smg 2, Smg 2 homolog nonsense mediated mRNA decay factor, UP Framesht 1, Up framesht mutation 1 homolog S. cerevisiae, Up framesht mutation 1 homolog, Up framesht suppressor 1 homolog, Up-framesht mutation 1 homolog S. cerevisiae, Up-framesht suppressor 1 homolog, UPF 1, UPF 1 regulator of nonsense transcripts homolog, UPF1.

Background: In eukaryotes, it is essential to have the ability to detect and degrade transcripts that lack full coding potential. Nonsense-mediated RNA decay (NMD) protects the organism by avoiding the translation of truncated peptides with dominant negative or deleterious gain-of-function potential. Rent1, a mammalian ortholog of Upflp, is essential for embryonic viability (13). Rent1 (also designated regulator of nonsense transcripts and HUpf1) contains an N-terminal zinc finger-like domain, NTPase domains and a region comprised of domains that define Rent1 as a superfamily group I helicase.

Gen-ID: 5976

Pathways: SARS-CoV-2 Protein Interaktom