Znf423 Antikörper (AA 901-1000)

Produktnummer ABIN1385826

Dieses Anti-Znf423-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Znf423 in ELISA, IHC (p), ICC, IF (cc), IF (p) und IHC (fro). Geeignet für Ratte.

Kurzübersicht für Znf423 Antikörper (AA 901-1000) (ABIN1385826)

Target: Znf423 (Zinc Finger Protein 423 (Znf423))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Znf423 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-Znf423 Antikörper

Bindungsspezifität: AA 901-1000

Spezifität: This antibody may also detect the protein Midasin if used in Human.

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Chicken,Zebrafish

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ZNF423/OAZ

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu Znf423

Target: Znf423 (Zinc Finger Protein 423 (Znf423))

Andere Bezeichnung: ZNF423/OAZ

Hintergrund:

Synonyms: OAZ, Roaz, hOAZ, Ebfaz, JBTS19, NPHP14, ZFP423, Zfp104, Zinc finger protein 423, Olf1/EBF-associated zinc finger protein, Smad- and Olf-interacting zinc finger protein, ZNF423, KIAA0760

Background: Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation, this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes. Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. Controls proliferation and differentiation of neural precursors in cerebellar vermis formation.

Gen-ID: 23090

UniProt: Q2M1K9