ENTPD2 Antikörper (AA 401-495)

Produktnummer ABIN1385820

Dieses Anti-ENTPD2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ENTPD2 in WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) und ICC. Geeignet für Ratte. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für ENTPD2 Antikörper (AA 401-495) (ABIN1385820)

Target: ENTPD2 (Ectonucleoside Triphosphate diphosphohydrolase 2 (ENTPD2))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ENTPD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Produktdetails anti-ENTPD2 Antikörper

Bindungsspezifität: AA 401-495

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Cow,Sheep,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ENTPD2/CD39L1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-ENTPD2 Antikörper (ABIN1385820)

Hwang, Dornbos, Steidemann, Dunivin, Rizzo, LaPres: "Mitochondrial-targeted aryl hydrocarbon receptor and the impact of 2,3,7,8-tetrachlorodibenzo-p-dioxin on cellular respiration and the mitochondrial proteome." in: Toxicology and applied pharmacology, (2016) (PubMed).

Details zu ENTPD2

Target: ENTPD2 (Ectonucleoside Triphosphate diphosphohydrolase 2 (ENTPD2))

Andere Bezeichnung: ENTPD2/CD39L1

Hintergrund:

Synonyms: CD39 antigen like 1, CD39 antigen-like 1, CD39 like1, CD39L1, CD39like1, ecto ATP diphosphohydrolase 2, ecto ATPase 2, ecto ATPDase 2, Ecto-ATP diphosphohydrolase 2, Ecto-ATPase 2, Ecto-ATPDase 2, ectoATPase 2, ectoATPDase 2, Ectonucleoside triphosphate diphosphohydrolase 2, ENTP2_HUMAN, Entpd2, NTPDase 2, NTPDase2.

Background: CD39, also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENP1), is an integral membrane glycoprotein that acts as an extracellular nucleotide-hydrolyzing enzyme. CD39 inhibits ADP-induced platelet aggregation by hydrolyzing ADP to AMP and ultimately generating adenosine. Intracellular CD39 undergoes glycosylation at 6 N-glycosylation sites and translocates to the membrane in order to be an active enzyme. CD39L1 is a 495 amino acid multi-pass membrane protein that requires calcium and magnesium cofactors to hydrolyze ATP and other nucleotides in the regulation of purigenic neurotransmission. CD39L1 is expressed in kidney, colon, heart, testis, pancreas, brain, prostate, skeletal muscle, small intestine and ovaries. There are two isoforms of CD39L1 that are produced as a result of alternative splicing events.