UBE2A Antikörper (AA 81-152)

Produktnummer ABIN1385809

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch UBE2A in ELISA, IF (cc), IF (p), IHC (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für UBE2A Antikörper (AA 81-152) (ABIN1385809)

Target: UBE2A (ube2a) (Ubiquitin-Conjugating Enzyme E2A (ube2a))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBE2A Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-UBE2A Antikörper

Bindungsspezifität: AA 81-152

Homologie: Human,Mouse,Rat,Cow,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human UBE2A/RAD6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu UBE2A

Target: UBE2A (ube2a) (Ubiquitin-Conjugating Enzyme E2A (ube2a))

Andere Bezeichnung: UBE2A

Hintergrund:

Synonyms: BHR6A, hHR6A, HR6A, mHR6A, RAD6 homolog A, RAD6A, RAD6B, UBC-1, UBC2, UBC6, UBCD6, UBE2A, UBE2A_HUMAN, UBE2B, Ubiquitin carrier protein A, Ubiquitin carrier protein, Ubiquitin conjugating enzyme E2 17 kDa, Ubiquitin conjugating enzyme E2 21.5 kDa, Ubiquitin conjugating enzyme E2 A, Ubiquitin protein ligase A, Ubiquitin-conjugating enzyme E2 A, Ubiquitin-conjugating enzyme E2-17 kDa, Ubiquitin-conjugating enzyme E2-21.5 kDa, Ubiquitin-protein ligase A.

Background: The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. The first step requires the ATP-dependent activation of the Ub C-terminus and the assembly of multi-Ub chains by the Ub-activating enzyme known as the E1 component. The Ub chain is then conjugated to the Ub-conjugating enzyme (E2) to generate an intermediate Ub-E2 complex. The Ub-ligase (E3) then catalyzes the transfer of Ub from E2 to the appropriate protein substrate. UBE2A (Ubiquitin-conjugating enzyme E2 A) and UBE2B (Ubiquitin-conjugating enzyme E2 B) are both Ub-conjugating enzymes that are essential to postreplication repair of UV-damaged DNA. UBE2A and UBE2B are both nuclear and cell membrane proteins that have been found to interact with Rad18.

Gen-ID: 7319