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Chromosome 12 Open Reading Frame 53 (C12orf53) Antikörper Primary Antibody

C12orf53 Reaktivität: Human, Maus, Ratte IF (p), IHC (p), WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1385798
$339.90
Zzgl. Versandkosten $45.00
100 μL
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 4 bis 6 Werktagen
  • Target
    Chromosome 12 Open Reading Frame 53 (C12orf53)
    Reaktivität
    Human, Maus, Ratte
    • 32
    • 25
    • 17
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Wirt
    Kaninchen
    Klonalität
    Polyklonal
    Konjugat
    Unkonjugiert
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Applikation
    Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    • 20
    • 14
    • 14
    • 14
    • 12
    • 3
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human C12ORF53
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:100-1000
    IHC-P 1:100-500
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C
    Haltbarkeit
    12 months
  • Target
    Chromosome 12 Open Reading Frame 53 (C12orf53)
    Andere Bezeichnung
    C12ORF53 (C12orf53 Antibody Abstract)
    Synonyme
    C12orf53, PANP, leda-1, PILR alpha associated neural protein, PIANP
    Hintergrund

    Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The C12orf53 gene product has been provisionally designated C12orf53 pending further characterization.

    Subcellular location: Extracellular

    Synonyms: Chromosome 12 open reading frame 53, DKFZp547D2210, Hypothetical protein LOC196500, Uncharacterized protein C12orf53, PIANP_HUMAN.

    Gen-ID
    196500
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