UBE2L6 Antikörper (AA 21-120)

Produktnummer ABIN1385712

Produktdetails anti-UBE2L6 Antikörper

Target: UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))

Bindungsspezifität: AA 21-120

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBE2L6 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Ratte

Homologie: Human,Mouse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Ube2L6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu UBE2L6

Target: UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))

Andere Bezeichnung: Ube2L6 (UBE2L6 Produkte)

Synonyme: UBE2L6 antikoerper, RIG-B antikoerper, UBCH8 antikoerper, 2810489I21Rik antikoerper, Ubce8 antikoerper, Ubcm8 antikoerper, UbcM8 antikoerper, ubiquitin conjugating enzyme E2 L6 antikoerper, ubiquitin-conjugating enzyme E2L 6 antikoerper, UBE2L6 antikoerper, Ube2l6 antikoerper

Hintergrund:

Synonyms: Retinoic acid induced gene B protein, Retinoic acid-induced gene B protein, RIG B, RIG-B, UB2L6_HUMAN, UBCH 8, UBCH8, UBE2L6, Ubiquitin carrier protein, Ubiquitin carrier protein L6, Ubiquitin conjugating enzyme E2L 6, Ubiquitin protein ligase, Ubiquitin protein ligase L6, Ubiquitin-protein ligase L6, Ubiquitin/ISG15 conjugating enzyme E2 L6, Ubiquitin/ISG15-conjugating enzyme E2 L6.

Background: Ubiquitin is an abundant, highly conserved protein found in all eukaryotic cells, either free or covalently attached to cellular proteins. The primary function of ubiquitin in mammalian systems is to clear abnormal, foreign, and improperly folded proteins by targeting them for proteosome degradation. Ubiquitin conjugating enzyme 8 (UBC8) is an E2 enzyme involved in the ubiquitin pathway for protein degradation. Like other E2 enzymes, UBC8 forms a thioester bond with ubiquitin in an E1-dependent manner. UBC8 binds to the human homolog of Drosophila ariadne (HHARI) and UBC7-associated protein (H7-AP1) as well as double ring-finger protein (Dorfin). UBC8 is enriched in the central nervous system and interacts with Parkin, a RING-finger-containing protein implicated in the pathogenesis of familial Parkinson?s disease. Parkin shares sequence homology with other UBC8 binding proteins such as HHARI and H7-AP1.

Gen-ID: 9246