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HEY2 Antikörper

HEY2 Reaktivität: Human, Maus, Ratte WB, IF (p), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1385664
  • Target Alle HEY2 Antikörper anzeigen
    HEY2 (Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2))
    Reaktivität
    • 47
    • 30
    • 18
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 46
    • 3
    • 1
    Kaninchen
    Klonalität
    • 49
    • 1
    Polyklonal
    Konjugat
    • 26
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HEY2 Antikörper ist unkonjugiert
    Applikation
    • 48
    • 19
    • 18
    • 12
    • 5
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human HEY2
    Isotyp
    IgG
    Top Product
    Discover our top product HEY2 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    HEY2 (Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2))
    Andere Bezeichnung
    HEY2 (HEY2 Produkte)
    Synonyme
    CHF1 antikoerper, GRIDLOCK antikoerper, GRL antikoerper, HERP1 antikoerper, HESR2 antikoerper, HRT2 antikoerper, bHLHb32 antikoerper, Herp1 antikoerper, Hrt2 antikoerper, hesr2 antikoerper, grl antikoerper, zgc:136746 antikoerper, hes related family bHLH transcription factor with YRPW motif 2 antikoerper, hairy/enhancer-of-split related with YRPW motif 2 antikoerper, hes-related family bHLH transcription factor with YRPW motif 2 antikoerper, HEY2 antikoerper, Hey2 antikoerper, hey2 antikoerper
    Hintergrund

    Synonyms: bHLHb32, Cardiovascular helix loop helix factor 1, Cardiovascular helix-loop-helix factor 1, CHF1, Class B basic helix-loop-helix protein 32, GRIDLOCK, GRL, Hairy and enhancer of split related 2, Hairy and enhancer of split-related protein 2, Hairy related transcription factor 2, Hairy-related transcription factor 2, Hairy/enhancer-of-split related with YRPW mot protein 2, hCHF1, HERP, HERP1, HES related repressor protein 1, HES-related repressor protein 2, HESR-2, HESR2, HEY2, HEY2_HUMAN, hHRT2, HRT-2, HRT2, Protein gridlock homolog.

    Background: The LIN-12/Notch family of transmembrane receptors plays a central role in development by regulating cell fate and establishing boundaries of gene expression. Notch signaling activates the Hairy/Enhancer of split (HES) genes, which encode basic helix-loop-helix (bHLH) transcriptional repressors that are critical for directing embryonic patterning and development. The Hairy-related transcription factors (HRTs) comprise a subclass of bHLH proteins that exhibit structural similarity with the HES proteins and include HRT1, HRT2 and HRT3. The HRT family (also designated Hesr, Hey, CHF and Gridlock) contain a bHLH domain, an Orange domain and a novel YRPW domain, which is absent in HRT3. The Hairy-related genes map to human chromosomes 8q21, 6q21 and 1p34.3 for HRT1, HRT2 and HRT3, respectively, and are downstream targets for Notch signaling. HRT1 is expressed in the somitic mesoderm, central nervous system, kidney, heart, nasal epithelium and limb buds in murine embryos as well as in adult tissues. It has altered expression in many breast, lung and kidney tumors. Like HRT1, HRT2 and HRT3 are also expressed in developing somites, heart and nervous system.

    Gen-ID
    23493
    Pathways
    Regulation of Muscle Cell Differentiation
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