RTP3 Antikörper (AA 21-120)

Produktnummer ABIN1385626

Produktdetails anti-RTP3 Antikörper

Target: RTP3 (Receptor (Chemosensory) Transporter Protein 3 (RTP3))

Bindungsspezifität: AA 21-120

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RTP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human

Homologie: Mouse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RTP3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu RTP3

Target: RTP3 (Receptor (Chemosensory) Transporter Protein 3 (RTP3))

Andere Bezeichnung: RTP3 (RTP3 Produkte)

Synonyme: Tmem7 antikoerper, LTM1 antikoerper, TMEM7 antikoerper, receptor (chemosensory) transporter protein 3 antikoerper, receptor transporter protein 3 antikoerper, Rtp3 antikoerper, RTP3 antikoerper

Hintergrund:

Synonyms: LTM1, Receptor chemosensory transporter protein 3, Receptor transporter protein 3, Receptor-transporting protein 3, RTP3, RTP3_HUMAN, TMEM7, Transmembrane protein 7.

Background: Members of the RTP (receptor transporter proteins) family have recently been discovered to influence bitter taste receptor expression in addition to inducing the expression of mammalian odorant receptors. RTP3 is a 232 amino acid single-pass type III membrane protein belonging to the TMEM7 family. Unlike other RTP proteins, RTP3 is not expressed in olfactory neurons but is expressed predominantly in liver. RTP3 is involved in the functional expression of bitter taste receptors and suppresses cell proliferation, and is also found in human circumvallate papillae and testis (regions where bitter taste receptors are expressed). The gene encoding RTP3 maps to human chromosome 3p21.31 within C3CER1 (chromosome 3 common eliminated region 1), which is frequently eliminated in chromosomal deletions of solid tumors.