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DAZL Antikörper (AA 51-130)

Der Kaninchen Polyklonal Anti-DAZL-Antikörper wurde für WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) und ICC validiert. Er ist geeignet, DAZL in Proben von Maus und Schaf zu detektieren. Es ist 1 Publikation verfügbar.
Produktnummer ABIN1385600

Kurzübersicht für DAZL Antikörper (AA 51-130) (ABIN1385600)

Target

Alle DAZL Antikörper anzeigen
DAZL (Deleted in Azoospermia-Like (DAZL))

Reaktivität

  • 30
  • 27
  • 17
  • 15
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Maus, Schaf

Wirt

  • 39
  • 3
  • 1
Kaninchen

Klonalität

  • 32
  • 11
Polyklonal

Konjugat

  • 18
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser DAZL Antikörper ist unkonjugiert

Applikation

  • 30
  • 13
  • 12
  • 12
  • 4
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
  • Bindungsspezifität

    • 14
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-130

    Kreuzreaktivität

    Maus, Schaf

    Homologie

    Human,Dog,Cow,Pig,Horse,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human DAZL

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Zhang, Zhao, Zhang, Hao, Yu, Min, Li, Ma, Chen, Yi, Tang, Meng, Liu, Wang, Shen, Zhang: "Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable." in: Chemosphere, Vol. 194, pp. 147-157, (2018) (PubMed).

  • Target

    DAZL (Deleted in Azoospermia-Like (DAZL))

    Andere Bezeichnung

    DAZL

    Hintergrund

    Synonyms: DAZ homolog, DAZ like autosomal, DAZ-like autosomal, deleted in azoospermia-like, DAZH, DAZL 1, DAZL, DAZL_HUMAN, DAZL1, DAZLA, Deleted in azoospermia like 1, Deleted in azoospermia like, Deleted in azoospermia like autosomal, Deleted in azoospermia-like 1, Deleted in azoospermia-like, Germline specic RNA binding protein, MGC26406, Spermatogenesis gene on the Y like autosomal, SPGY like autosomal, SPGY-like-autosomal, SPGYLA, Tpx2.

    Background: The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010].

    Gen-ID

    1618
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