ARNTL2 Antikörper (AA 381-480)

Produktnummer ABIN1385567

Der Kaninchen Polyklonal Anti-ARNTL2-Antikörper wurde für WB, ELISA, IF (cc), IF (p), IHC (p), ICC und IHC (fro) validiert. Er ist geeignet, ARNTL2 in Proben von Human zu detektieren.

Kurzübersicht für ARNTL2 Antikörper (AA 381-480) (ABIN1385567)

Target: ARNTL2 (Aryl Hydrocarbon Receptor Nuclear Translocator-Like 2 (ARNTL2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARNTL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-ARNTL2 Antikörper

Bindungsspezifität: AA 381-480

Homologie: Human,Mouse,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ARNTL2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu ARNTL2

Target: ARNTL2 (Aryl Hydrocarbon Receptor Nuclear Translocator-Like 2 (ARNTL2))

Andere Bezeichnung: ARNTL2/BMAL2

Hintergrund:

Synonyms: ARNT L2, ARNTL 2, ARNTL2, ARNTL2 protein, Aryl hydrocarbon receptor nuclear translocator like 2, Aryl hydrocarbon receptor nuclear translocator like protein 2, Aryl hydrocarbon receptor nuclear translocator-like 2, Basic helix loop helix PAS protein MOP9, Basic-helix-loop-helix-PAS protein MOP9, bHLHe6, BMA L2, BMAL 2, BMAL2, Brain and muscle ARNT like 2, Brain and muscle ARNT-like 2, CL, CYCLE like factor, CYCLE-like factor, Member of PAS protein 9, MGC124257, MGC149671, MGC149672, MGC158186, MOP 9, MOP9, PASD 9, PASD9, Transcription factor BMAL 2, Transcription factor BMAL2, wu:fj90c09, BMAL2_HUMAN.

Background: BMAL2 is a 636 amino acid protein that localizes to the nucleus and contains one bHLH (basic helix-loop-helix) domain, one PAC (PAS-associated C-terminal) domain and two PAS (PER-ARNT-SIM) domains. Expressed at high levels in placenta and brain and at lower levels in liver, thymus, heart, lung and kidney, BMAL2 functions as a component of the circadian core oscillator, which includes a variety of proteins that work in tandem to activate the transcription of target genes. More specifically, BMAL2, when functioning as a component of the core oscillator, binds to the E-box element (3'-CACGTG-5') of target DNA, thus inducing transcription. Multiple isoforms of BMAL2 exist due to alternative splicing events.

Gen-ID: 56938

Pathways: Photoperiodism