C19orf28 Antikörper

Produktnummer ABIN1385462

Produktdetails anti-C19orf28 Antikörper

Target: C19orf28 (Chromosome 19 Open Reading Frame 28 (C19orf28))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C19orf28 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MFSD12/C19orf28

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu C19orf28

Target: C19orf28 (Chromosome 19 Open Reading Frame 28 (C19orf28))

Andere Bezeichnung: C19orf28 (C19orf28 Produkte)

Synonyme: MGC81076 antikoerper, C19orf28 antikoerper, PP3501 antikoerper, F630110N24Rik antikoerper, Wdt1 antikoerper, major facilitator superfamily domain containing 12 L homeolog antikoerper, major facilitator superfamily domain containing 12 antikoerper, mfsd12.L antikoerper, mfsd12 antikoerper, MFSD12 antikoerper, Mfsd12 antikoerper

Hintergrund:

Synonyms: Chromosome 19 open reading frame 28, Hypothetical protein LOC126321, MGC20700, PP3501, Uncharacterized MFS type transporter C19orf28, MFS12_HUMAN.

Background: C19orf28, also known as PP3501, is a multi-pass membrane protein that belongs to the major facilitator superfamily. The gene encoding C19orf28 localizes to chromosome 19 and, due to alternative splicing events, C19orf28 exists as two isoforms. Consisting of around 63 million bases with over 1,400 genes, chromosome 19 makes up over 2 % of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fc receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3. The C19orf28 gene product has been provisionally designated C19orf28 pending further characterization.