MUC1 Antikörper (AA 941-1040)
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- Target Alle MUC1 Antikörper anzeigen
- MUC1 (Mucin 1 (MUC1))
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Bindungsspezifität
- AA 941-1040
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MUC1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Human
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human MUC1
- Isotyp
- IgG
- Top Product
- Discover our top product MUC1 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- MUC1 (Mucin 1 (MUC1))
- Andere Bezeichnung
- MUC1 (MUC1 Produkte)
- Synonyme
- CA 15-3 antikoerper, CD227 antikoerper, EMA antikoerper, H23AG antikoerper, KL-6 antikoerper, MAM6 antikoerper, MCKD1 antikoerper, MUC-1 antikoerper, MUC-1/SEC antikoerper, MUC-1/X antikoerper, MUC1/ZD antikoerper, PEM antikoerper, PEMT antikoerper, PUM antikoerper, Muc-1 antikoerper, mucin 1, cell surface associated antikoerper, mucin 1, transmembrane antikoerper, MUC1 antikoerper, Muc1 antikoerper
- Hintergrund
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Synonyms: Breast carcinoma associated antigen DF3, Breast carcinoma associated antigen DF3, Breast carcinoma-associated antigen DF3, CA 15 3, CA 15-3, CA15 3, CA15 3 antigen, CA15.3, Cancer antigen 15-3, Carcinoma associated mucin, Carcinoma associated mucin, Carcinoma-associated mucin, CD 227, CD227, CD227, CD227 antigen, DF3 antigen, DF3 antigen, EMA, EMA, Episialin, Episialin, Epithelial membrane antigen, Epithelial membrane antigen, Epithelial mucin tandem repeat sequence, H23 antigen, H23 antigen, H23AG, H23AG, HGNC:7508, KL 6, KL-6, KL6, Krebs von den Lungen-6, MAM 6, MAM6, MUC 1, MUC 1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1, MUC1-alpha, MUC1-beta, MUC1-CT, MUC1-NT, MUC1/ZD, MUC1_HUMAN, Mucin 1, Mucin 1 precursor, Mucin 1 transmembrane, Mucin-1 subunit beta, Mucin1, Mucin1, Peanut reactive urinary mucin, Peanut reactive urinary mucin, Peanut-reactive urinary mucin, PEM, PEMT, PEMT, Polymorphic epithelial mucin, Polymorphic epithelial mucin, PUM, PUM, Tumor associated epithelial membrane antigen, Tumor associated epithelial membrane antigen, Tumor associated epithelial mucin, Tumor associated mucin, Tumor associated mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin.
Background: MUC1 is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoietic cell lineages. It is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. It is expressed abundantly in lactating mammary glands and overexpressed abundantly in >90 % breast carcinomas and metastases. Transgenic MUC1 has been shown to associate with all four cebB receptors and localize with erbB1 (EGFR) in lactating glands. The MUC1 gene contains seven exons and produces several different alternatively spliced variants. The major expressed form of MUC1 uses all seven exons and is a type 1 transmembrane protein with a large extracellular tandem repeat domain. The tandem repeat domain is highly O glycosylated and alterations in glycosylation have been shown in epithelial cancer cells.
- Gen-ID
- 4582
- Pathways
- Negative Regulation of intrinsic apoptotic Signaling
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