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beta 2 Defensin Antikörper (AA 24-64)

Dieses Anti-beta 2 Defensin-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von beta 2 Defensin in IF (cc), IF (p), ICC, ELISA, IHC (p) und IHC (fro). Geeignet für Ratte. Dieses Primary Antibody wurde in 1 Publikation zitiert.
Produktnummer ABIN1385259

Kurzübersicht für beta 2 Defensin Antikörper (AA 24-64) (ABIN1385259)

Target

Alle beta 2 Defensin (BD-2) Antikörper anzeigen
beta 2 Defensin (BD-2) (Defensin beta 2 (BD-2))

Reaktivität

  • 37
  • 31
  • 18
  • 5
  • 2
  • 2
  • 1
Ratte

Wirt

  • 61
  • 14
  • 4
  • 2
Kaninchen

Klonalität

  • 66
  • 14
Polyklonal

Konjugat

  • 30
  • 7
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
Dieser beta 2 Defensin Antikörper ist unkonjugiert

Applikation

  • 43
  • 38
  • 38
  • 20
  • 17
  • 15
  • 13
  • 11
  • 9
  • 5
  • 4
  • 1
  • 1
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 32
    • 16
    • 10
    • 2
    • 1
    AA 24-64

    Kreuzreaktivität

    Ratte

    Homologie

    Human

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human beta 2 Defensin

    Isotyp

    IgG
  • Applikationshinweise

    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Al-Samadi, Salem, Ainola, Hietanen, Häyrinen-Immonen, Konttinen: "Increased beta 2 defensin in recurrent aphthous ulcer." in: Oral diseases, (2014) (PubMed).

  • Target

    beta 2 Defensin (BD-2) (Defensin beta 2 (BD-2))

    Hintergrund

    Synonyms: BD-2, SAP1, DEFB2, DEFB4, HBD-2, DEFB-2, DEFB12, Beta-defensin 4A, Beta-defensin 2, Defensin, beta 2, Skin-antimicrobial peptide 1, DEFB4A

    Background: Beta-defensins (also designated BD, and hBD in human) are small cationic peptides with broad-spectrum antimicrobial activity. Produced in mucosal epithelia and neutrophils of several species, Beta-defensins are developmentally regulated. Human b-defensin 2 is locally regulated by inflammation and is the first member of the b-defensin family that is locally inducible by inflammation. The murine homolog of human b-defensin 2, which is called b-defensin 3, is present in the respiratory system and in low levels in the epithelial cells of the intestine and lung. The unique murine b-defensin 2 (Defb2) is not expressed in airways of untreated mice, but is upregulated in the airways by lipopolysaccharide and may contribute to host defense at the mucosal surface of the airways

    Gen-ID

    1673

    UniProt

    O15263
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