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UTF1 Antikörper (Undifferentiated Embryonic Cell Transcription Factor 1) AA 101-170 Primary Antibody

UTF1 Reaktivität: Human ELISA, ICC, IF (cc), IF (p), IHC (fro), IHC (p), WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1385234
$374.00
Zzgl. Versandkosten $45.00
100 μL
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 4 bis 6 Werktagen
  • Target Alle UTF1 Antikörper anzeigen
    UTF1
    Bindungsspezifität
    • 15
    • 14
    • 8
    • 8
    • 7
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-170
    Reaktivität
    • 57
    • 15
    • 9
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 42
    • 9
    • 8
    • 1
    Kaninchen
    Klonalität
    • 52
    • 8
    Polyklonal
    Konjugat
    • 21
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser UTF1 Antikörper ist unkonjugiert
    Applikation
    • 43
    • 31
    • 12
    • 12
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Homologie
    Mouse,Rat,Cow
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human UTF1
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    UTF1
    Andere Bezeichnung
    UTF1 (UTF1 Produkte)
    Synonyme
    AI505934, undifferentiated embryonic cell transcription factor 1, UTF1, Utf1, LOC616910
    Hintergrund

    UTF1 is a 341 amino acid protein that localizes to the nucleus and is subject to post-translational phosphorylation. Associating with the TFIID complex via an interaction with the TATA box binding protein (TFIID), UTF1 binds to the N-terminal region of ATF-2 and, via this binding, acts as a transcriptional coactivator of ATF-2, thereby enhancing transcriptional activity. Human UTF1 shares 64 % homology with its mouse counterpart, suggesting a similar role between species. The gene encoding UTF1 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5 % of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman?s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.

    Subcellular location: Nucleus

    Synonyms: hUTF 1, hUTF1, Undferentiated embryonic cell transcription factor 1, UTF 1, UTF1, UTF1_HUMAN.

    Gen-ID
    8433
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