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GPRC5A Antikörper (G Protein-Coupled Receptor, Family C, Group 5, Member A) AA 1-33 Primary Antibody

GPRC5A Reaktivität: Human ELISA, FACS, ICC, IF (cc), IF (p), IHC (fro), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1385196
$374.00
Zzgl. Versandkosten $45.00
100 μL
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 4 bis 6 Werktagen
  • Target Alle GPRC5A Antikörper anzeigen
    GPRC5A
    Bindungsspezifität
    • 15
    • 13
    • 9
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-33
    Reaktivität
    • 65
    • 16
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 62
    • 3
    Kaninchen
    Klonalität
    • 64
    • 1
    Polyklonal
    Konjugat
    • 31
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GPRC5A Antikörper ist unkonjugiert
    Applikation
    • 36
    • 24
    • 14
    • 12
    • 12
    • 10
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human RAI3
    Isotyp
    IgG
  • Applikationshinweise
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    GPRC5A
    Andere Bezeichnung
    RAI3 (GPRC5A Produkte)
    Synonyme
    GPCR5A, RAI3, RAIG1, Rai3, Raig1, G protein-coupled receptor class C group 5 member A, G protein-coupled receptor, family C, group 5, member A, G protein-coupled receptor, class C, group 5, member A, GPRC5A, Gprc5a
    Hintergrund

    RAI3 is an transmembrane G-protein-coupled receptor that affects many essential biological processes including embryogenesis, cell growth, differentiation, and apoptosis. RAI3 may also be involved in maintaining homeostasis of epithelial cells. Retinoic acid receptors directly regulate RAI3 during its transcription in embryonal carcinoma differentiation. RAI3 expression is upregulated in most tumor cell lines that express mutant p53, suggesting that p53 interacts with the promoter of RAI3 and represses its expression at the beginning of apoptosis. RAI3 is a potential molecular target for diagnosing breast cancer, and selective suppression of signals from RAI3 may have a place in breast cancer treatments.

    Subcellular location: Cytoplasm, Cell membrane

    Synonyms: G protein coupled receptor family C group 5 member A, G-protein coupled receptor family C group 5 member A, GPCR 5A, GPCR5A, Gprc 5a, Gprc5a, Orphan G protein coupling receptor PEIG 1, Orphan G protein coupling receptor PEIG1, Orphan G-protein-coupling receptor PEIG-1, RAI 3, RAI3_HUMAN, Raig 1, RAIG-1, Raig1, Retinoic acid induced 3, Retinoic acid induced gene 1 protein, Retinoic acid induced protein 3, Retinoic acid responsive, Retinoic acid responsive gene, Retinoic acid-induced gene 1 protein, Retinoic acid-induced protein 3.

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