Procollagen Type 2A (AA 1-100) Antikörper

Produktnummer ABIN1385152

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Procollagen Type 2A in IF (cc), IF (p), ELISA, IHC (fro), IHC (p) und ICC. Es zeigt Reaktivität gegenüber Proben von Zebrafisch (Danio rerio).Es wurde in 1 Publikation zitiert.

Kurzübersicht für Procollagen Type 2A (AA 1-100) Antikörper (ABIN1385152)

Target: Procollagen Type 2A

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Produktdetails

Bindungsspezifität: AA 1-100

Kreuzreaktivität: Zebrafisch (Danio rerio)

Homologie: Human,Dog,Cow,Sheep,Pig,Chicken,Rabbit,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Collagen II alpha 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen

Tarafder, Gulko, Sim, Yang, Cook, Lee: "Engineered Healing of Avascular Meniscus Tears by Stem Cell Recruitment." in: Scientific reports, Vol. 8, Issue 1, pp. 8150, (2018) (PubMed).

Antigendetails

Target: Procollagen Type 2A

Hintergrund:

Synonyms: Collagen II N-terminal propeptide, Collagen II alpha 1, COL2A1, COL2A1 protein, collagen, type II, alpha 1, collagen alpha-1II, type II collagen, alpha-1 type II collagen, alpha1 type II collagen, Col2a1, AOM, Cartilage collagen, COL11A3, Collagen alpha 1II chain precursor, Collagen II alpha 1 polypeptide, Collagen type II alpha 1 primary osteoarthritis spondyloepiphyseal dysplasia congenital, MGC131516, SEDC, Collagen alpha-1II chain, Alpha-1 type II collagen, CO2A1_HUMAN.

Background: Collagen type II is the most abundant protein of cartilage matrix. Two isoforms exist and collagen type IIA is involved in early development of cartilage in embryos. The collagen is produced from type II procollagen when two teloterminal propeptides are digested from the precursor and released into the circulation. Procollagen type II N-terminal propeptide is considered a marker of cartilage synthesis and the normal concentration in serum is approximately 30 ng/mL.