CD4 Antikörper (PE)

Produktnummer ABIN135728

Für dieses Produkt ist 1 Publikation verfügbar. Der Maus-Monoklonal Anti-CD4-Antikörper wurde für FACS validiert. Er ist geeignet zum Nachweis von CD4 in Proben aus Human. }

Kurzübersicht für CD4 Antikörper (PE) (ABIN135728)

Target: CD4

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD4 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: RFT4

Produktdetails anti-CD4 Antikörper (PE)

Spezifität: Human CD4, Mr 55 kDa

Produktmerkmale: Mouse Anti-Human CD4-PE

Immunogen: Thymocyte and E-rosetted lymphocytes

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , ICC - Reported in literature , WB - Reported in literature , Sep - Reported in literature
• Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, PE, PE/TXRD, APC, SPRD, CY5, PE/CY5.5, 10 L/106 cells PE/CY7, APC/CY7, AF488, AF647, and AF700 conjugates For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 100 tests in 1.0 mL of PBS/Sodium azide and a stabilizing agent

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze!
Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C

Referenzen für anti-CD4 Antikörper (PE) (ABIN135728)

Kim, Kim, Shin, Jung, Choi, Jun: "Expression patterns of programmed death-1 and programmed death-1 ligand-1 on T cells in gastric cancer." in: Oncology letters, Vol. 18, Issue 3, pp. 2661-2669, (2019) (PubMed).

Details zu CD4

Target: CD4

Andere Bezeichnung: CD4

Hintergrund: D4 is a 59 kDa type I transmembrane glycoprotein and a member of the Ig-SF of cell surface receptors. It is expressed predominantly on the helper/inducer subpopulation of mature T lymphocytes, and on monocytes and macrophages. Domains 1 and 2 bind to MHC Class II antigens, while domains 3 and 4 may be involved in cis interactions with the CD3/TCR complex. CD4 functions as an accessary molecule in the recognition of foreign antigens in association with MHC Class II antigens by T cells.

Pathways: T-Zell Rezeptor Signalweg, Maintenance of Protein Location, CXCR4-mediated Signaling Events