CD4 Antikörper
Kurzübersicht für CD4 Antikörper (ABIN135725)
Target
Alle CD4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- Human CD4, Mr 55 kDa
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Produktmerkmale
- Mouse Anti-Human CD4-UNLB
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Aufreinigung
- Purified
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Immunogen
- Thymocyte and E-rosetted lymphocytes
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Isotyp
- IgG1
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Applikationshinweise
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- Applications: FC - Quality tested , IHC-FS - Reported in literature , ICC - Reported in literature , WB - Reported in literature , Sep - Reported in literature
- Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, PE, PE/TXRD, APC, SPRD, CY5, PE/CY5.5, 10 L/106 cells PE/CY7, APC/CY7, AF488, AF647, and AF700 conjugates For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
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Probenmenge
- 1 mL
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.1 mg/mL
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Buffer
- 0.1 mg of purified immunoglobulin in 1.0 mL of borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added
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Konservierungsmittel
- Without preservative
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Handhabung
- Each reagent is stable for the period shown on the bottle label if stored as directed.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2-8°C
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- CD4
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Andere Bezeichnung
- CD4
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Hintergrund
- D4 is a 59 kDa type I transmembrane glycoprotein and a member of the Ig-SF of cell surface receptors. It is expressed predominantly on the helper/inducer subpopulation of mature T lymphocytes, and on monocytes and macrophages. Domains 1 and 2 bind to MHC Class II antigens, while domains 3 and 4 may be involved in cis interactions with the CD3/TCR complex. CD4 functions as an accessary molecule in the recognition of foreign antigens in association with MHC Class II antigens by T cells.
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Pathways
- T-Zell Rezeptor Signalweg, Maintenance of Protein Location, CXCR4-mediated Signaling Events
Target
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