P-Selectin Antikörper (PE)

Produktnummer ABIN135715

Dieser Maus Monoklonal Antikörper erkennt spezifisch P-Selectin in FACS. Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für P-Selectin Antikörper (PE) (ABIN135715)

Target: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser P-Selectin Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: 1-2B6

Produktdetails anti-P-Selectin Antikörper (PE)

Spezifität: Human CD62E & CD62P/Porcine CD62E, Mr 97 kDa/140 kDa

Produktmerkmale: Mouse Anti-Human CD62E/CD62P-PE

Aufreinigung: Ion exchange.

Immunogen: TNF stimulated human endothelial cells

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , WB-NR - Reported in literature , ELISA - Reported in literature , Block - Reported in literature , Adhesion - Reported in literature
• Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, PE, APC, SPRD, and AF700 conjugates 10 L/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Kommentare:

Inhibition of activity

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 100 tests in 1.0 mL of PBS/Sodium azide and a stabilizing agent

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze!
Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C

Referenzen für anti-P-Selectin Antikörper (PE) (ABIN135715)

Fink, Schwarz, Feldbra: "Severe endothelial injury and subsequent repair in patients after successful cardiopulmonary resuscitation." in: Critical care, Vol. 14, Issue 3, pp. R104, (2010) (PubMed).

Details zu P-Selectin

Target: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Andere Bezeichnung: CD62E/CD62P

Hintergrund: CD62E represents the 100-110 kDa type I transmembrane glycoprotein E-selectin, also known as endothelial-leukocyte adhesion molecule-1 (ELAM-1). It is expressed on cytokine-stimulated endothelium, weakly on unactivated endothelium, and is absent on leukocytes. Like other selectins, CD62E is an adhesion molecule that contributes to the initial attachment and rolling of leukocytes on endothelial surfaces, a prerequisite for leukocyte extravasation into tissues.