P-Selectin Antikörper
Kurzübersicht für P-Selectin Antikörper (ABIN135713)
Target
Alle P-Selectin (SELP) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- Human CD62E & CD62P/Porcine CD62E, Mr 97 kDa/140 kDa
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Produktmerkmale
- Mouse Anti-Human CD62E/CD62P-UNLB
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Aufreinigung
- Purified
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Immunogen
- TNF stimulated human endothelial cells
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Isotyp
- IgG1
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Applikationshinweise
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- Applications: FC - Quality tested , IHC-FS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , WB-NR - Reported in literature , ELISA - Reported in literature , Block - Reported in literature , Adhesion - Reported in literature
- Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, PE, APC, SPRD, and AF700 conjugates 10 L/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
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Kommentare
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Inhibition of activity
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Probenmenge
- 1 mL
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.1 mg/mL
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Buffer
- 0.1 mg of purified immunoglobulin in 1.0 mL of borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added
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Konservierungsmittel
- Without preservative
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Handhabung
- Each reagent is stable for the period shown on the bottle label if stored as directed.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2-8°C
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- P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))
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Andere Bezeichnung
- CD62E/CD62P
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Hintergrund
- CD62E represents the 100-110 kDa type I transmembrane glycoprotein E-selectin, also known as endothelial-leukocyte adhesion molecule-1 (ELAM-1). It is expressed on cytokine-stimulated endothelium, weakly on unactivated endothelium, and is absent on leukocytes. Like other selectins, CD62E is an adhesion molecule that contributes to the initial attachment and rolling of leukocytes on endothelial surfaces, a prerequisite for leukocyte extravasation into tissues.
Target
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