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MCAM Antikörper

Dieses Maus Monoklonal-Antikörper erkennt spezifisch MCAM in FACS. Er zeigt eine Reaktivität gegenüber Huhn.
Produktnummer ABIN135586

Kurzübersicht für MCAM Antikörper (ABIN135586)

Target

Alle MCAM Antikörper anzeigen
MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Reaktivität

  • 185
  • 62
  • 54
  • 15
  • 15
  • 8
  • 7
  • 6
  • 5
  • 2
Huhn

Wirt

  • 111
  • 108
  • 8
  • 2
  • 1
  • 1
Maus

Klonalität

  • 132
  • 99
Monoklonal

Konjugat

  • 98
  • 17
  • 16
  • 11
  • 8
  • 6
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser MCAM Antikörper ist unkonjugiert

Applikation

  • 113
  • 100
  • 92
  • 43
  • 33
  • 32
  • 32
  • 24
  • 12
  • 12
  • 5
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

Klon

C264
  • Spezifität

    Chicken/Turkey MCAM, Mr 98 kDa

    Produktmerkmale

    Mouse Anti-Chicken MCAM-UNLB

    Aufreinigung

    Purified

    Immunogen

    Mixture of E15 and E16 thymocytes from H.B15, H.B19, and H.B21 chicken embryos

    Isotyp

    IgG2b
  • Applikationshinweise

    • Applications: FC - Quality tested , ICC - Reported in literature , IP - Reported in literature
    • Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC and BIOT conjugates 1 g/106 cells PE conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

    Probenmenge

    1 mL

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    0.5 mg/mL

    Buffer

    0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

    Konservierungsmittel

    Without preservative

    Handhabung

    Each reagent is stable for the period shown on the bottle label if stored as directed.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store at 2-8°C
  • Target

    MCAM (Melanoma Cell Adhesion Molecule (MCAM))

    Andere Bezeichnung

    MCAM

    Hintergrund

    Chicken MCAM, a member of the immunoglobulin superfamily of cell surface receptors, consists of the V-V-C2-C2-C2 Ig domains. It is a single chain glycoprotein with three mRNA splice variants. One has a short cytoplasmic tail, another has a long tail, and the third seems to lack transmembrane and cytoplasmic regions. It is highly homologous to gicerin, a molecule involved in neurite outgrowth and Wilm's kidney tumor progression in the chicken, and to the human melanoma progression molecule MUC18. Chicken MCAM is expressed by c-kit+ hematopoietic progenitor cells in embryonic bone marrow, thymocytes, and capillary endothelial cells. MCAM-expressing cells sorted from bone marrow are enriched in progenitors capable of differentiating into T cells when transferred into the appropriate thymic microenvironment. MCAM has been proposed to be involved in cellular adhesion and homing processes.
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