MCAM Antikörper
Kurzübersicht für MCAM Antikörper (ABIN135586)
Target
Alle MCAM Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- Chicken/Turkey MCAM, Mr 98 kDa
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Produktmerkmale
- Mouse Anti-Chicken MCAM-UNLB
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Aufreinigung
- Purified
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Immunogen
- Mixture of E15 and E16 thymocytes from H.B15, H.B19, and H.B21 chicken embryos
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Isotyp
- IgG2b
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Applikationshinweise
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- Applications: FC - Quality tested , ICC - Reported in literature , IP - Reported in literature
- Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC and BIOT conjugates 1 g/106 cells PE conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
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Probenmenge
- 1 mL
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- 0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added
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Konservierungsmittel
- Without preservative
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Handhabung
- Each reagent is stable for the period shown on the bottle label if stored as directed.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2-8°C
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- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
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Andere Bezeichnung
- MCAM
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Hintergrund
- Chicken MCAM, a member of the immunoglobulin superfamily of cell surface receptors, consists of the V-V-C2-C2-C2 Ig domains. It is a single chain glycoprotein with three mRNA splice variants. One has a short cytoplasmic tail, another has a long tail, and the third seems to lack transmembrane and cytoplasmic regions. It is highly homologous to gicerin, a molecule involved in neurite outgrowth and Wilm's kidney tumor progression in the chicken, and to the human melanoma progression molecule MUC18. Chicken MCAM is expressed by c-kit+ hematopoietic progenitor cells in embryonic bone marrow, thymocytes, and capillary endothelial cells. MCAM-expressing cells sorted from bone marrow are enriched in progenitors capable of differentiating into T cells when transferred into the appropriate thymic microenvironment. MCAM has been proposed to be involved in cellular adhesion and homing processes.
Target
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