CD28 Antikörper
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- Target Alle CD28 Antikörper anzeigen
- CD28
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Reaktivität
- Huhn
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD28 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS)
- Spezifität
- Chicken/Turkey CD28, Mr 40-44 kDa
- Produktmerkmale
- Mouse Anti-Chicken CD28-UNLB
- Aufreinigung
- Purified
- Immunogen
- Chicken peripheral blood lymphocytes
- Klon
- AV7
- Isotyp
- IgG1
- Top Product
- Discover our top product CD28 Primärantikörper
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- Applikationshinweise
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- Applications: FC - Quality tested , IHC-FS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , Costim - Reported in literature
- Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE conjugate 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
- Kommentare
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In vitro T-cell costimulation
- Probenmenge
- 1 mL
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- 0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added
- Konservierungsmittel
- Without preservative
- Handhabung
- Each reagent is stable for the period shown on the bottle label if stored as directed.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C
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Pathogenic and immunogenic responses in turkeys following in ovo exposure to avian metapneumovirus subtype C." in: Veterinary immunology and immunopathology, (2010) (PubMed).
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Pathogenic and immunogenic responses in turkeys following in ovo exposure to avian metapneumovirus subtype C." in: Veterinary immunology and immunopathology, (2010) (PubMed).
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- Target
- CD28
- Andere Bezeichnung
- CD28 (CD28 Produkte)
- Synonyme
- Tp44 antikoerper, CD28RNA antikoerper, cd28 antikoerper, CD28 molecule antikoerper, CD28 antigen antikoerper, Cd28 molecule antikoerper, CD28 molecule L homeolog antikoerper, CD28 antikoerper, Cd28 antikoerper, cd28.L antikoerper
- Hintergrund
- Chicken CD28 antigen is a type I transmembrane monomeric glycoprotein which does not contain the cysteine residues that form disulfide-linked covalent homodimers found in the mammalian counterpart. This may reduce the avidity of binding to individual ligand molecules expected to be present on Ag presenting cells. Peripheral + T cells are CD28-negative.1 Monoclonal antibodies against CD28 have a costimulatory effect on T cells stimulated by phorbol myristate acetate (PMA), concanavalin A or MAbs against the avian T cell receptor (TCR). Both V1- and V2-expressing cells respond equally well to stimulation with anti-CD28 in combination with PMA. These responses are resistant to cyclosporin A, but inhibited by herbimycin A, suggesting that CD28 employs a signalling pathway at least partly distinct from that triggered by TCR/CD3.
- Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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