CD8 alpha Antikörper (FITC)

Produktnummer ABIN135513

Produktdetails anti-CD8 alpha Antikörper (FITC)

Target: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Reaktivität: Huhn

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD8 alpha Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Spezifität: Chicken/Turkey/Guinea Fowl/Pigeon CD8α, Mr 34 kDa

Produktmerkmale: Mouse Anti-Chicken CD8a-FITC

Aufreinigung: Ion Exchange

Immunogen: Chicken thymocytes and Ig-negative blood leukocytes

Klon: CT-8

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , IHC-PS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , Block - Reported in literature
• Working Dilutions: Flow Cytometry FITC, BIOT, AF488, and PACBLU conjugates 1 g/106 cells PE and CY5 conjugates 0.2 g/106 cells APC, SPRD, AF647, and AF700 conjugates 0.1 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Probenmenge: 1 mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: 0.5 mg in 1.0 mL of PBS/Sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C

Referenzen für anti-CD8 alpha Antikörper (FITC) (ABIN135513)

Lacharme-Lora, Chaloner, Gilroy, Humphrey, Gibbs, Jopson, Wright, Reid, Ketley, Humphrey, Williams, Rushton, Wigley: "B lymphocytes play a limited role in clearance of Campylobacter jejuni from the chicken intestinal tract." in: Scientific reports, Vol. 7, pp. 45090, (2018) (PubMed).

Parvizi, Andrzejewski, Read, Behboudi, Sharif: "Expression profiling of genes associated with regulatory functions of T-cell subsets in Marek's disease virus-infected chickens." in: Avian pathology : journal of the W.V.P.A, Vol. 39, Issue 5, pp. 367-73, (2010) (PubMed).

Details zu CD8 alpha

Target: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Andere Bezeichnung: CD8a (CD8A Produkte)

Hintergrund: CD8 In the chicken, the CD8 molecule is present in two forms: (i) a homodimer of two chains, and (ii) a heterodimer of an chain and a chain. While the vast majority of CD8+ cells in the thymus, spleen, and blood of adult chickens express both CD8- and CD8-chains, a relatively large proportion of the CD8+ TCR- cells in the spleens of embryos and young chicks express only the -chain of CD8. Among intestinal epithelial lymphocytes, the major CD8+ T cell populations present in mice are conserved, but there is a population of TCR- CD8 cells in the chicken that is not found in rodents. Chicken CD8 is expressed on approximately 80 % of thymocytes, 15 % of blood mononuclear cells and 50 % of spleen cells, but < 1 % of cells in the bursa and bone marrow.

Pathways: T-Zell Rezeptor Signalweg