L-Selectin Antikörper

Produktnummer ABIN135253

Dieser Ratte Monoklonal Antikörper detektiert spezifisch L-Selectin in FACS, IP, IHC (fro), BR und CyTox. Es zeigt Reaktivität gegenüber Proben von Maus.

Kurzübersicht für L-Selectin Antikörper (ABIN135253)

Target: L-Selectin (SELL) (Selectin L (SELL))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser L-Selectin Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Reagent (BR), Cytotoxicity Test (CyTox)

Klon: MEL-14

Produktdetails anti-L-Selectin Antikörper

Verwendungszweck: Rat Anti-Mouse CD62L-LE/AF

Spezifität: Mouse CD62L, Mr 74 kDa on lymphocytes and Mr 95 kDa on neutrophils

Produktmerkmale: Low Endotoxin/Azide Free Anti-Mouse CD62L antibody for use in flow cytometry, immunohistochemistry, immunoprecipitation, blocking, and cytotoxicity assays.

Endotoxin-Niveau: Low Endotoxin

Immunogen: C3H/eb cloned mouse B cell lymphoma 38C-13

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Konservierungsmittel: Azide free

Handhabung: Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C

Details zu L-Selectin

Target: L-Selectin (SELL) (Selectin L (SELL))

Andere Bezeichnung: CD62L

Hintergrund: CD62L, also known as L-selectin, is a type I transmembrane glycoprotein with lectin-like and Epidermal Growth Factor-like domains. It binds to sialylated oligosaccharide determinants on high endothelial venules (HEV) in peripheral lymph nodes. In the mouse, CD62L is expressed on most thymocytes and on peripheral leukocytes, including B and T lymphocytes, neutrophils, monocytes and eosinophils. This member of the selectin family of cell adhesion molecules appears to be required for lymphocyte homing to peripheral lymph nodes and for leukocyte extravasation at sites of inflammation. Expression of CD62L on lymphocytes and neutrophils is rapidly down-regulated upon cell activation and the level of CD62L expression, along with other markers, distinguishes naive T cells from effector/memory T cells.

Gen-ID: 20343

UniProt: P18337