ICAM1 Antikörper
Kurzübersicht für ICAM1 Antikörper (ABIN135246)
Target
Alle ICAM1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- Mouse/Porcine CD54, Mr 95 kDa
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Produktmerkmale
- Rat Anti-Mouse CD54-UNLB
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Aufreinigung
- Purified
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Immunogen
- Mouse NS-1 cells
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Isotyp
- IgG2b
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Applikationshinweise
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- Applications: FC - Quality tested , IHC-FS - Reported in literature , ICC - Reported in literature , WB - Reported in literature , IP - Reported in literature , Block - Reported in literature , Purification - Reported in literature
- Working Dilutions: Flow Cytometry FITC, BIOT, AF488, and PACBLU conjugates 1 g/106 cells PE, APC, AF647, and AF700 conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
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Kommentare
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In vitro blocking studies
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Probenmenge
- 1 mL
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- 0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added
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Konservierungsmittel
- Without preservative
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Handhabung
- Each reagent is stable for the period shown on the bottle label if stored as directed.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2-8°C
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Coxsackievirus and adenovirus receptor mediates the responses of endothelial cells to fluid shear stress." in: Experimental & molecular medicine, Vol. 51, Issue 11, pp. 1-15, (2020) (PubMed).
: "
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Coxsackievirus and adenovirus receptor mediates the responses of endothelial cells to fluid shear stress." in: Experimental & molecular medicine, Vol. 51, Issue 11, pp. 1-15, (2020) (PubMed).
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- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
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Andere Bezeichnung
- CD54
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Hintergrund
- CD54, a member of the immunoglobulin superfamily of cell surface receptors and also known as Intercellular Adhesion Molecule-1 (ICAM-1), is a type I transmembrane glycoprotein that mediates important cell/cell interactions. CD54 is expressed on endothelial cells, dendritic cells, keratinocytes and lymphocytes. Its expression is upregulated by inflammatory mediators such as IFN-γ, IL-1, TNF-α, lipopolysaccharide and phorbol esters. Endothelial CD54 contributes to the extravasation of leukocytes from blood vessels, particularly in areas of inflammation. CD54 on antigen-presenting cells contributes to antigen-specific T-cell activation, presumably by enhancing interactions between T cell and antigen-presenting cells. These adhesion reactions are mediated via the binding of CD54 to its major ligands, LFA-1 and Mac-1.
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
Target
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