Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

ICAM1 Antikörper

Dieses Anti-ICAM1-Antikörper ist ein Ratte Monoklonal-Antikörper zur Detektion von ICAM1 in FACS. Geeignet für Maus. Dieses Primary Antibody wurde in 1 Publikation zitiert.
Produktnummer ABIN135246

Kurzübersicht für ICAM1 Antikörper (ABIN135246)

Target

Alle ICAM1 Antikörper anzeigen
ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Reaktivität

  • 232
  • 52
  • 24
  • 23
  • 11
  • 7
  • 4
  • 3
  • 1
  • 1
Maus

Wirt

  • 156
  • 111
  • 26
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Ratte

Klonalität

  • 192
  • 108
  • 2
Monoklonal

Konjugat

  • 156
  • 25
  • 25
  • 19
  • 15
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ICAM1 Antikörper ist unkonjugiert

Applikation

  • 168
  • 141
  • 108
  • 70
  • 67
  • 50
  • 46
  • 31
  • 30
  • 26
  • 15
  • 14
  • 12
  • 10
  • 6
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

Klon

YN1-1-7-4
  • Spezifität

    Mouse/Porcine CD54, Mr 95 kDa

    Produktmerkmale

    Rat Anti-Mouse CD54-UNLB

    Aufreinigung

    Purified

    Immunogen

    Mouse NS-1 cells

    Isotyp

    IgG2b
  • Applikationshinweise

    • Applications: FC - Quality tested , IHC-FS - Reported in literature , ICC - Reported in literature , WB - Reported in literature , IP - Reported in literature , Block - Reported in literature , Purification - Reported in literature
    • Working Dilutions: Flow Cytometry FITC, BIOT, AF488, and PACBLU conjugates 1 g/106 cells PE, APC, AF647, and AF700 conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

    Kommentare

    In vitro blocking studies

    Probenmenge

    1 mL

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    0.5 mg/mL

    Buffer

    0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

    Konservierungsmittel

    Without preservative

    Handhabung

    Each reagent is stable for the period shown on the bottle label if stored as directed.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store at 2-8°C
  • Chung, Kim, An, Lee, Lim, Kang, Kwon: "Coxsackievirus and adenovirus receptor mediates the responses of endothelial cells to fluid shear stress." in: Experimental & molecular medicine, Vol. 51, Issue 11, pp. 1-15, (2020) (PubMed).

  • Target

    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

    Andere Bezeichnung

    CD54

    Hintergrund

    CD54, a member of the immunoglobulin superfamily of cell surface receptors and also known as Intercellular Adhesion Molecule-1 (ICAM-1), is a type I transmembrane glycoprotein that mediates important cell/cell interactions. CD54 is expressed on endothelial cells, dendritic cells, keratinocytes and lymphocytes. Its expression is upregulated by inflammatory mediators such as IFN-γ, IL-1, TNF-α, lipopolysaccharide and phorbol esters. Endothelial CD54 contributes to the extravasation of leukocytes from blood vessels, particularly in areas of inflammation. CD54 on antigen-presenting cells contributes to antigen-specific T-cell activation, presumably by enhancing interactions between T cell and antigen-presenting cells. These adhesion reactions are mediated via the binding of CD54 to its major ligands, LFA-1 and Mac-1.

    Pathways

    Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
Sie sind hier:
Chat with us!