CD32/CD16 Antikörper

Produktnummer ABIN135200

Der Ratte Monoklonal anti-CD32/CD16 Antikörper wird verwendet zum Nachweis von CD32/CD16 in Proben von Maus. Er wurde validiert für FACS, IP, BR und IHC (fro).

Kurzübersicht für CD32/CD16 Antikörper (ABIN135200)

Target: CD32/CD16

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD32/CD16 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Blocking Reagent (BR), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: 93

Produktdetails anti-CD32/CD16 Antikörper

Verwendungszweck: Rat Anti-Mouse CD16/32-LE/AF

Spezifität: Mouse CD16/32

Produktmerkmale: Low Endotoxin/Azide Free Anti-Mouse CD16/32 antibody for use in flow cytometry, immunohistochemistry, immunoprecipitation, and blocking assays.

Endotoxin-Niveau: Low Endotoxin

Immunogen: VH81X Tg B cells and T220 stromal cell line

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Konservierungsmittel: Azide free

Handhabung: Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C

Details zu CD32/CD16

Target: CD32/CD16

Andere Bezeichnung: CD16/32

Hintergrund: The lymphocyte Fc receptors recognize the Fc portion of IgG, presented either as immune complexes or as free antibody. The different classes of receptors are distinct because of varying size, tissue distribution and affinity for IgGs. The Fc type II receptor is expressed on a wide variety of cells including B cells, hematopoietic cells, monocyte/macrophages, neutrophils, platelets, Langerhans cells, eosinophils, basophils, trophoblasts, and endothelial cells of the placenta. The Fc type III receptors are higher affinity than the type II and are expressed on macrophages, NK cells and neutrophils. Both types of receptors can be expressed on the same cell and in varying ratios. The receptors are constitutively expressed, although cytokines and lymphokines can modulate their expression.4 Besides identifying FcR+ cells, monoclonal antibodies to the FcII/III receptor have been used to block Fc receptor binding of IgG, Fc-mediated signal transduction and effector functions, clearance of immune complexes and to attenuate infection by organisms dependent on FcR for parasitic invasion.

Gen-ID: 14131

UniProt: P08508