CD28 Antikörper
Kurzübersicht für CD28 Antikörper (ABIN135188)
Target
Alle CD28 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Hamster Anti-Mouse CD28-LE/AF
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Spezifität
- Mouse CD28, Mr 40 kDa
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Produktmerkmale
- Low Endotoxin/Azide Free Anti-Mouse CD28 antibody for use in flow cytometry, immunoprecipitation, costimulation, and stimulation assays.
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Endotoxin-Niveau
- Low Endotoxin
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Immunogen
- C57BL/6N mouse T cell lymphoma EL4 cell line
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Phosphate buffered saline, pH 7.4
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Konservierungsmittel
- Azide free
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Handhabung
- Each reagent is stable for the period shown on the bottle label if stored as directed.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- 2-8°C
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- CD28
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Andere Bezeichnung
- CD28
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Hintergrund
- CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes, and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. CD28 is a ligand for CD80/B7-1 and CD86/B7-2 on B cells and other antigen presenting cells, and plays an important role in the interaction between T cells and B cells. CD28 is a co-stimulatory receptor involved in many, but not all, T-cell independent immune responses.
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Gen-ID
- 12487
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UniProt
- P31041
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Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
Target
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