ITGA4 Antikörper
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- Target Alle ITGA4 Antikörper anzeigen
- ITGA4 (Integrin alpha 4 (ITGA4))
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Reaktivität
- Maus
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser ITGA4 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS)
- Spezifität
- Mouse/Human CD49d, Mr 150 kDa
- Produktmerkmale
- Rat Anti-Mouse CD49d-LE/AF
- Endotoxin-Niveau
- Low endotoxin
- Immunogen
- P815 cells
- Klon
- PS-2
- Isotyp
- IgG2b
- Top Product
- Discover our top product ITGA4 Primärantikörper
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anti-Integrin alpha 4 (ITGA4) (Internal Region) antibody
ITGA4 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin alpha 4 (ITGA4) antibodyITGA4 Reaktivität: Human FACS, WB, ELISA Wirt: Maus Monoclonal 5C4 unconjugated
anti-Integrin alpha 4 (ITGA4) (AA 551-650) antibodyITGA4 Reaktivität: Human, Maus, Kaninchen FACS, WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin alpha 4 (ITGA4) (AA 833-977) antibodyITGA4 Reaktivität: Human FACS, WB, ELISA Wirt: Maus Monoclonal 7E4C5 unconjugated
anti-Integrin alpha 4 (ITGA4) (AA 376-558) antibodyITGA4 Reaktivität: Human IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin alpha 4 (ITGA4) (C-Term) antibodyITGA4 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin alpha 4 (ITGA4) antibodyITGA4 Reaktivität: Human WB, IHC, IP Wirt: Kaninchen Monoclonal unconjugated
anti-Integrin alpha 4 (ITGA4) antibodyITGA4 Reaktivität: Human FACS, WB, EIA Wirt: Maus Monoclonal 5C4 unconjugated
anti-Integrin alpha 4 (ITGA4) antibodyITGA4 Reaktivität: Maus FACS, IP, IHC (fro) Wirt: Ratte Monoclonal R1-2 unconjugated
anti-Integrin alpha 4 (ITGA4) antibodyITGA4 Reaktivität: Maus FACS, IP, IHC (fro), Func Wirt: Ratte Monoclonal DATK32 unconjugated
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- Applikationshinweise
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- Applications: FC - Quality tested , IHC-FS - Reported in literature , IP - Reported in literature , Adhesion - Reported in literature , Block - Reported in literature
- Working Dilutions: Flow Cytometry FITC and BIOT conjugates 2 g/106 cells PE conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
- Probenmenge
- 1 mL
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- 0.5 mg of purified immunoglobulin in 1.0 mL of PBS
- Konservierungsmittel
- Azide free
- Handhabung
- Each reagent is stable for the period shown on the bottle label if stored as directed.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.
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- Target
- ITGA4 (Integrin alpha 4 (ITGA4))
- Andere Bezeichnung
- CD49d (ITGA4 Produkte)
- Hintergrund
- CD49d, the 4 chain (100 kDa) of the VLA-4 integrin heterodimer (Mr 150 kDa) VLA-4 belongs to the 1-integrin family, which functions both as cell-matrix and cell-cell receptors.1-3 As a matrix receptor VLA-4 binds to an alternatively spliced domain of fibronectin, while as a cellular receptor it associates with its counter-receptor ligand VCAM-1. In addition to CD44/pgp-1, VLA-4 has been shown to be important for lymphopoiesis, and is also believed to be important for extravasation of lymphocytes into sites of inflammation as a second signal in addition to LFA/ICAM-1. CD49d/VLA-4 is expressed in low amounts on resting lymphocytes and monocytes, is absent or minimally detectable on stromal cells, whereas virtually all lymphoid and myeloid cells in bone marrow and in long-term culture are positive.
- Pathways
- Integrin Complex
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