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Fibrillin Antikörper (FITC)

Dieses Anti-Fibrillin-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Fibrillin in IHC und ICC. Geeignet für Rind (Kuh) und Human.
Produktnummer ABIN135063

Kurzübersicht für Fibrillin Antikörper (FITC) (ABIN135063)

Target

Fibrillin (FBL)

Reaktivität

Rind (Kuh), Human

Wirt

  • 5
Maus

Klonalität

  • 5
Monoklonal

Konjugat

  • 2
  • 2
  • 1
Dieser Fibrillin Antikörper ist konjugiert mit FITC

Applikation

  • 5
  • 5
  • 3
  • 2
Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Klon

11C1-3
  • Produktmerkmale

    The antibody detects: Human and bovine fibrillin (Mr 350 kDa), other species not tested
    In immunohistochemical staining of paraformaldehyde-fixed human skin, mAb 11C1.3 labels the elastic framework and more specifically the oxytalantic network close to the epidermis. The antibody also exhibits discrete staining of normal fibroblasts in culture and of extracellular (elastin) fibrils in a variety of tissues. There is an aberrant expression of fibrillin in Marfan syndrome.

    Immunogen

    Microfibrils from zonular apparatus of bovine eye Ig

    Isotyp

    IgG1
  • Applikationshinweise

    Working Dilution:
    Immunohistochemistry: 1:50-1:100 (30-60 min at RT)
    Representative data are included in this product insert.

    Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

    Probenmenge

    1 mL

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    Product is supplied as 0.2 mg in 1.0 mL of PBS / NaN3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

    Handhabung

    Protect conjugated products from light.
    Each reagent is stable for the period shown on the bottle label if stored as directed.

    Lagerung

    4 °C
  • Target

    Fibrillin (FBL)

    Andere Bezeichnung

    Fibrillin

    Hintergrund

    The fibrillins are extracellular matrix glycoproteins which occur as a major component of a subset of connective tissue microfibrils. These microfibrils have a beaded appearance and a cross-sectional diameter of 10-12 nm. In elastic tissues, these structures are thought to provide the scaffold onto which elastin is assembled to form elastic fibers, although their function in non-elastic tissues is unclear.
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