KCNT1 Antikörper (AA 1168-1237)

Produktnummer ABIN1304962

Dieses Maus Monoklonal-Antikörper erkennt spezifisch KCNT1 in WB, IHC und ICC. Er zeigt eine Reaktivität gegenüber Ratte.

Kurzübersicht für KCNT1 Antikörper (AA 1168-1237) (ABIN1304962)

Target: KCNT1 (Potassium Channel, Subfamily T, Member 1 (KCNT1))

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser KCNT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Klon: N3-26

Produktdetails anti-KCNT1 Antikörper

Bindungsspezifität: AA 1168-1237

Spezifität: No off-targets reported

Kreuzreaktivität: Human, Marine Mollusks (Liolophura), Maus, Ratte

Produktmerkmale:

Description: Our Anti-Slo2.2/Slack K+ channel mouse monoclonal primary antibody is produced in-house from hybridoma clone N3/26. It is KO validated, detects human, marine mollusk, mouse, and rat Slo2.2/Slack K+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Manufacturer Comment: We produce our Slo2.2/Slack K+ channel mouse monoclonal primary antibody from hybridoma clone N3/26. It is great in IHC, ICC, WB and is purified by Protein A chromatography.

Aufreinigung: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.

Reinheit: > 90% specific antibody

Immunogen: Fusion protein amino acids 1168-1237 of rat Slo2.2 (accession number NP_068625) produced recombinantly in E. Coli

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

Dilution Range: IHC: 1:400

Dilution Range: ICC: 1:250

Dilution Range: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Haltbarkeit: 24 months

Details zu KCNT1

Target: KCNT1 (Potassium Channel, Subfamily T, Member 1 (KCNT1))

Andere Bezeichnung: Slo2.2

Hintergrund:

Synonyms: Potassium channel subfamily T member 1 (Sequence like a calcium-activated potassium channel subunit)

Target Description: Potassium channel subfamily T member 1 or -KCNT1/Slo2.2/Slack K+ channel is encoded by the gene KCNT1. Slo2.2 is a member of the the voltage-gated ion channel (vic) superfamily, and the KCNT protein family, which is made of KCNT1 and KCNT2. Slo2.2 functions as an outwardly rectifying potassium channel subunit to contribute to ion conductance and signaling pathways. Slo2.2 can be activated by high intracellular sodium or chloride levels. Slo2.2 is expressed at the membrane in many areas of the brain, brainstem, spinal cord, spleen and liver. Mutations in this gene cause the early-onset epileptic disorders

Gene Name Alternatives: Kcnt1 Slack

Molekulargewicht: 140 kDa

NCBI Accession: NP_068625