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DLG1 Antikörper (AA 1-104)

Dieses Maus Monoklonal-Antikörper erkennt spezifisch DLG1 in WB, IHC, IP und ICC. Er zeigt eine Reaktivität gegenüber Ratte.
Produktnummer ABIN1304944

Kurzübersicht für DLG1 Antikörper (AA 1-104) (ABIN1304944)

Target

Alle DLG1 Antikörper anzeigen
DLG1 (Discs, Large Homolog 1 (DLG1))

Reaktivität

  • 23
  • 16
  • 8
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Ratte

Wirt

  • 20
  • 13
  • 1
  • 1
Maus

Klonalität

  • 20
  • 15
Monoklonal

Konjugat

  • 27
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser DLG1 Antikörper ist unkonjugiert

Applikation

  • 23
  • 12
  • 12
  • 8
  • 7
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Klon

K64-15
  • Bindungsspezifität

    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-104

    Spezifität

    No off-targets reported for PSD-95, Chapsyn-110 and SAP102 expressed in transfected cells

    Kreuzreaktivität

    Human, Maus, Ratte

    Produktmerkmale

    Description: Our Anti-SAP97 mouse monoclonal primary antibody is produced in-house from hybridoma clone K64/15. It is KO validated, detects human, mouse, and rat SAP97, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.

    Manufacturer Comment: We produce our SAP97 mouse monoclonal primary antibody from hybridoma clone K64/15. It is great in IHC, ICC, IP, WB and is purified by Protein A chromatography.

    Aufreinigung

    Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.

    Reinheit

    > 90% specific antibody

    Immunogen

    Fusion protein amino acids 1-104 (N-terminus) of rat SAP97 (accession number Q62696) produced recombinantly in E. Coli

    Isotyp

    IgG1
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

    Haltbarkeit

    24 months
  • Target

    DLG1 (Discs, Large Homolog 1 (DLG1))

    Andere Bezeichnung

    SAP97

    Hintergrund

    Synonyms: Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)

    Target Description: Synapse-associated protein 97, Discs Large MAGUK Scaffold Protein 1 or SAP97 is encoded by the gene DLG1. SAP97 is a member of the MAGUK (membrane-associated guanylate kinase) protein family. It is a multi-domain scaffolding protein which serves to recruit receptors channels and other signaling molecules to the plasma membrane. SAP97 is expressed in heart, lung, epithelial cells and brain. SAP97 may have a role in septate junction formation, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Diseases associated with DLG1 include Mayer-Rokitansky-Kuster-Hauser Syndrome and Depression.

    Gene Name Alternatives: Dlg1 Dlgh1

    Molekulargewicht

    130 kDa

    UniProt

    Q62696

    Pathways

    Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response
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