Neuroligin 1 Antikörper (AA 718-843)

Produktnummer ABIN1304857

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Neuroligin 1 in WB, IHC und ICC. Er zeigt eine Reaktivität gegenüber Ratte.

Kurzübersicht für Neuroligin 1 Antikörper (AA 718-843) (ABIN1304857)

Target: Neuroligin 1 (NLGN1)

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Neuroligin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Klon: N97A-31

Produktdetails anti-Neuroligin 1 Antikörper

Bindungsspezifität: AA 718-843

Spezifität: No off-targets reported for Neuroligin-2, -3, -4 or -4*

Kreuzreaktivität: Huhn, Human, Maus, Ratte

Produktmerkmale:

Description: Our Anti-Neuroligin-1 mouse monoclonal primary antibody is produced in-house from hybridoma clone N97A/31. It is KO validated, detects mouse and rat Neuroligin-1, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Manufacturer Comment: We produce our Neuroligin-1 mouse monoclonal primary antibody from hybridoma clone N97A/31. It is great in IHC, ICC, WB and is purified by Protein A chromatography.

Aufreinigung: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.

Reinheit: > 90% specific antibody

Immunogen: Fusion protein amino acids 718-843 (intracellular C-terminus) of rat Neuroligin-1 (accession number NP_446320) produced recombinantly in E. Coli

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

Dilution Range: IHC: 1:500

Dilution Range: ICC: 1:500

Dilution Range: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Haltbarkeit: 24 months

Details zu Neuroligin 1

Target: Neuroligin 1 (NLGN1)

Andere Bezeichnung: Neuroligin-1

Hintergrund:

Synonyms: Neuroligin-1 (Neuroligin I)

Target Description: Neuroligin 1 is a member of a large family of alternatively sliced proteins located at the post synaptic surface in the central nervous system, and stains as a post synaptic marker. Neuroligin 1 is involved in cell-cell-interactions by binding to neurexin family members and other postsynaptic proteins to localize receptors and channels in the postsynaptic density. Suggested roles for Neuroligin 1 include synapse function and synaptic signal transmission and maintaining synapse integrity. Mutations in Neuroligans have been implicated in autism and other cognitive disorders.

Gene Name Alternatives: Nlgn1

Molekulargewicht: 120 kDa

NCBI Accession: NP_446320

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis