CNTNAP2 Antikörper (Extracellular Domain)

Produktnummer ABIN1304573

Der Maus Monoklonal Anti-CNTNAP2-Antikörper wurde für WB, IHC, ICC und IP validiert. Er ist geeignet, CNTNAP2 in Proben von Human zu detektieren.

Kurzübersicht für CNTNAP2 Antikörper (Extracellular Domain) (ABIN1304573)

Target: CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CNTNAP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Klon: K67-25

Produktdetails anti-CNTNAP2 Antikörper

Bindungsspezifität: Extracellular Domain

Spezifität: No off-targets reported for Caspr/paranodin

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale:

Description: Our Anti-CASPR2 mouse monoclonal primary antibody is produced in-house from hybridoma clone K67/25. It is KO validated, detects human, mouse, and rat CASPR2, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.

Manufacturer Comment: We produce our CASPR2 mouse monoclonal primary antibody from hybridoma clone K67/25. It is great in IHC, ICC, IP, WB and is purified by Protein A chromatography.

Aufreinigung: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.

Reinheit: > 90% specific antibody

Immunogen: Fusion protein 96-1265 (extracellular domain) of human Caspr2 (accession number A0A090N7T7) produced recombinantly in E. Coli

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

Dilution Range: IHC: 1:100

Dilution Range: WB: 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Haltbarkeit: 24 months

Details zu CNTNAP2

Target: CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))

Andere Bezeichnung: CASPR2

Hintergrund:

Synonyms: Contactin associated protein-like 2 (Contactin associated protein-like 2, isoform CRA_b)

Target Description: Contactin-associated protein-like 2 protein, or Caspr2, is a neuronal transmembrane member of the Neurexin family. Structural features of Caspr2 include epidermal growth factor repeats, laminin G domains, F5/8 type C domain, fibrinogen-like domains, and PDZ binding sites. Caspr2 is a cell adhesion molecule as well as a receptor. It is involved in mediating cell-cell interactions in the nervous system and involved in neural-glia interactions and clustering of potassium channels in myelinated axons. It is expressed at the juxaperanodal region of nodes of Ranvier in the CNS and PNS. Changes in expression have been associated with increased susceptibility to autism and epilepsy.

Gene Name Alternatives: CNTNAP2 hCG_15499 tcag7.496

Molekulargewicht: 180 kDa

NCBI Accession: NP_054860