CNTNAP1 Antikörper (Cytoplasmic Domain)

Produktnummer ABIN1304571

Dieses Anti-CNTNAP1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CNTNAP1 in WB, IHC, IP und ICC. Geeignet für Ratte. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für CNTNAP1 Antikörper (Cytoplasmic Domain) (ABIN1304571)

Target: CNTNAP1 (Contactin Associated Protein 1 (CNTNAP1))

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CNTNAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Klon: K65-35

Produktdetails anti-CNTNAP1 Antikörper

Bindungsspezifität: Cytoplasmic Domain

Spezifität: No off-targets reported

Kreuzreaktivität: Wüstenrennmaus, Human, Maus, Ratte

Produktmerkmale:

Description: Our Anti-CASPR/Neurexin IV mouse monoclonal primary antibody is produced in-house from hybridoma clone K65/35. It is KO validated, detects gerbil, human, mouse, and rat CASPR/Neurexin IV, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.

Manufacturer Comment: We produce our CASPR/Neurexin IV mouse monoclonal primary antibody from hybridoma clone K65/35. It is great in IHC, ICC, IP, WB and is purified by Protein A chromatography.

Aufreinigung: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.

Reinheit: > 90% specific antibody

Immunogen: Fusion protein 1308-1381 (cytoplasmic domain) of rat Caspr (accession number P97846) produced recombinantly in E. Coli

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

Dilution Range: IHC: 1:250

Dilution Range: ICC: 1:500

Dilution Range: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Haltbarkeit: 24 months

Referenzen für anti-CNTNAP1 Antikörper (ABIN1304571)

McGonigal, Barrie, Yao, Black, McLaughlin, Willison: "Neuronally expressed a-series gangliosides are sufficient to prevent the lethal age-dependent phenotype in GM3-only expressing mice." in: Journal of neurochemistry, (2021) (PubMed).

Details zu CNTNAP1

Target: CNTNAP1 (Contactin Associated Protein 1 (CNTNAP1))

Andere Bezeichnung: Neurexin IV

Hintergrund:

Synonyms: Contactin-associated protein 1 (Caspr) (Caspr1) (Neurexin IV) (Neurexin-4) (Paranodin) (p190)

Target Description: CASPR (Neurexin IV) is part of the neurexin family, which includes presynaptic proteins located in the presynaptic membrane of the brain.

Gene Name Alternatives: Cntnap1 Caspr Nrxn4

Molekulargewicht: 220 kDa

UniProt: P97846

Pathways: Cell-Cell Junction Organization