CASK Antikörper (AA 318-415)

Produktnummer ABIN1304569

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CASK in WB, IHC, ICC und IP. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CASK Antikörper (AA 318-415) (ABIN1304569)

Target: CASK (Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CASK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Klon: K56A-50

Produktdetails anti-CASK Antikörper

Bindungsspezifität: AA 318-415

Spezifität: No off-targets reported

Kreuzreaktivität: Huhn, Human, Maus, Ratte, Xenopus laevis, Zebrafisch (Danio rerio)

Produktmerkmale:

Description: Our Anti-CASK mouse monoclonal primary antibody is produced in-house from hybridoma clone K56A/50. It is KO validated, detects chicken, human, mouse, rat, Xenopus, and zebrafish CASK, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.

Manufacturer Comment: We produce our CASK mouse monoclonal primary antibody from hybridoma clone K56A/50. It is great in IHC, ICC, IP, WB and is purified by Protein A chromatography.

Aufreinigung: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.

Reinheit: > 90% specific antibody

Immunogen: Fusion protein amino acids 318-415 of rat CASK/Lin2 (accession number Q62915) produced recombinantly in E. Coli

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

Dilution Range: IHC: 1:500

Dilution Range: ICC: 1:500

Dilution Range: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Haltbarkeit: 24 months

Details zu CASK

Target: CASK (Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK))

Andere Bezeichnung: CASK

Hintergrund:

Synonyms: Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase) (Protein lin-2 homolog)

Target Description: Calcium/Calmodulin-Dependent Serine Protein Kinase or CASK scaffolding protein is encoded by the gene CASK. CASK is a member of the MAGUK (membrane-associated guanylate kinase) protein family. CASK is a a calcium/calmodulin-dependent serine protein kinase. CASK is found in many different tissues including kidney, lung, liver and brain. In the brain, CASK protein is located at synapses. CASK acts as a multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Mutations in this gene are associated with FG syndrome 4, microcephaly with pontine and cerebellar hypoplasia, and a form of X-linked intellectual disability.

Gene Name Alternatives: CASK LIN2

Molekulargewicht: 100 kDa

UniProt: Q62915

Pathways: Synaptic Vesicle Exocytosis