Ataxin 1 Antikörper (AA 746-761)

Produktnummer ABIN1304551

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Ataxin 1 in WB und ICC. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für Ataxin 1 Antikörper (AA 746-761) (ABIN1304551)

Target: Ataxin 1 (ATXN1)

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Ataxin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC)

Klon: N65-37

Produktdetails anti-Ataxin 1 Antikörper

Bindungsspezifität: AA 746-761

Spezifität: Minimal off target reactivity for S751A mutant of Ataxin-1 by ELISA and immunofluorescence and negative by immunoblot (right)

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale:

Description: Our Anti-Ataxin-1, WT mouse monoclonal primary antibody is produced in-house from hybridoma clone N65/37. It detects human, mouse, and rat Ataxin-1, WT, and is purified by Protein A chromatography. It is great for use in ICC, WB.

Manufacturer Comment: We produce our Ataxin-1, WT mouse monoclonal primary antibody from hybridoma clone N65/37. It is great in ICC, WB and is purified by Protein A chromatography.

Aufreinigung: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.

Reinheit: > 90% specific antibody

Immunogen: Synthetic peptide amino acids 746-761 (RKRRRWSAPETRKLEK) of mouse ataxin-1 (accession number P54254)

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Haltbarkeit: 24 months

Details zu Ataxin 1

Target: Ataxin 1 (ATXN1)

Andere Bezeichnung: Ataxin-1

Hintergrund:

Synonyms: Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog)

Target Description: Ataxin1, also known as spinocerebellar ataxia type 1 protein homolog, is a highly conserved DNA-binding protein. Ataxin1 is expressed in brain and can be found at high levels in the cortex and the hypothalamus in neurons. It is also expressed in other tissues. Within the cell, it is highly expressed in the nucleus, and can also be found in the cytoplasm. Mutations in the ataxin-1 gene cause spinocerebellar ataxia type 1.

Gene Name Alternatives: Atxn1 Sca1

Molekulargewicht: 85 kDa

UniProt: P54254

Pathways: Synaptic Membrane