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CD83 Antikörper (CD83) (PE) Primary Antibody

CD83 Reaktivität: Human, Non-Human Primate FACS, IHC (fro) Wirt: Maus Monoclonal HB15e PE
Produktnummer ABIN1303169
$484.24
Zzgl. Versandkosten $45.00
100 tests
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 5 bis 7 Werktagen
  • Target Alle CD83 Antikörper anzeigen
    CD83
    Reaktivität
    • 87
    • 46
    • 12
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Non-Human Primate
    Wirt
    • 59
    • 33
    • 17
    • 1
    Maus
    Klonalität
    • 55
    • 53
    Monoklonal
    Konjugat
    • 54
    • 14
    • 11
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD83 Antikörper ist konjugiert mit PE
    Applikation
    • 64
    • 33
    • 26
    • 15
    • 13
    • 7
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Spezifität
    The mouse monoclonal antibody HB15e recognizes CD83, a 40-45 kDa type I glycoprotein expressed on mature dendritic cells.
    HLDA IV., WS Code T 85
    Kreuzreaktivität (Details)
    Human, Non-Human Primates
    Immunogen
    Human CD83-transfected Cos cells
    Klon
    HB15e
    Isotyp
    IgG1
  • Applikationshinweise
    The reagent is designed for Flow Cytometry analysis of human blood cells using 10 μ,l reagent / 100 μ,l of whole blood or 106 cells in a suspension.The content of a vial (1 ml) is sufficient for 100 tests.
    Kommentare

    The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Rekonstitution
    No reconstitution is necessary.
    Buffer
    The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide.
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze.
    Avoid prolonged exposure to light.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
  • Target
    CD83
    Andere Bezeichnung
    CD83 (CD83 Produkte)
    Synonyme
    BL11, HB15, CD83 molecule, CD83 antigen, Cd83, CD83
    Hintergrund
    CD83 is a 40-45 kDa heavily glycosylated type I cell surface glycoprotein of immunoglobulin family. It is expressed on the surface of mature dendritic cells, Langerhans cells in the skin, and interdigitating reticulum cells in the lymphoid tissues. Low expression of CD83 has been reported in activated T and B cells. Cytoplasmic expression of CD83 can be detected also in monocytes and macrophages. CD83 is involved in modulation of antigen presentation. Soluble CD83 has immunoregulatory functions, it is able to down-regulate dendritic cell maturation and stimulation of T cells. In the developing immune system, release of soluble CD83 from dendritic cells upon stimulation by gram-positive or gram-negative bacteria has anti-allergic effect. Herpes simplex virus, on the other hand, causes CD83 degradation in mature dendritic cells.
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