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TCR alpha/beta Antikörper (T Cell Receptor alpha/beta) (Biotin) Primary Antibody

Reaktivität: Human FACS Wirt: Maus Monoclonal IP26 Biotin
Pubmed (3 references)
Produktnummer ABIN1302746
$417.45
Zzgl. Versandkosten $45.00
0.1 mg
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 5 bis 7 Werktagen
  • Target See all TCR alpha/beta products
    TCR alpha/beta
    Reaktivität
    • 21
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    Human
    Wirt
    • 42
    • 19
    Maus
    Klonalität
    • 61
    Monoklonal
    Konjugat
    • 26
    • 13
    • 9
    • 7
    • 2
    • 1
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    Dieser TCR alpha/beta Antikörper ist konjugiert mit Biotin
    Applikation
    • 56
    • 34
    • 29
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    • 16
    • 11
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    Flow Cytometry (FACS)
    Spezifität
    The mouse monoclonal antibody IP26 recognizes a monomorphic determinant of TCR alpha/beta, the dominant subtype of T cell receptor expressed in human peripheral blood.
    Kreuzreaktivität (Details)
    Human
    Klon
    IP26
    Isotyp
    IgG1
  • Applikationshinweise
    Biotinylated antibody is designed for indirect immunofluorescence analysis by Flow Cytometry.Suggested working dilution is 1:300. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.
    Kommentare

    The purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze.
    Avoid prolonged exposure to light.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
  • Kuttruff, Koch, Kelp, Pawelec, Rammensee, Steinle: "NKp80 defines and stimulates a reactive subset of CD8 T cells." in: Blood, Vol. 113, Issue 2, pp. 358-69, (2009) (PubMed).

    Ortonne, Huet, Gaudez, Marie-Cardine, Schiavon, Bagot, Musette, Bensussan: "Significance of circulating T-cell clones in Sezary syndrome." in: Blood, Vol. 107, Issue 10, pp. 4030-8, (2006) (PubMed).

    Huet, Bagot, Loyaux, Capdevielle, Conraux, Ferrara, Bensussan, Marie-Cardine: "SC5 mAb represents a unique tool for the detection of extracellular vimentin as a specific marker of Sezary cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 176, Issue 1, pp. 652-9, (2005) (PubMed).

  • Target
    TCR alpha/beta
    Andere Bezeichnung
    TCR alpha/beta (TCR alpha/beta Produkte)
    Hintergrund
    The antigen-specific T cell receptor (TCR) is composed of either alpha and beta subunit, or gamma and delta subunit. Majority of T cells present in the blood, lymph and secondary lymphoid organs express TCR alpha/beta heterodimers, whereas the T cells expressing TCR gamma/delta heterodimers are localized mainly in epithelial tissues and at the sites of infection. The subunits of TCR heterodimers are covalently bonded and in the endoplasmic reticulum they associate with CD3 subunits to form functional TCR-CD3 complex. Lack of expression of any of the chains is sufficient to stop cell surface expression.
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